The Atlanta Journal-Constitution

Next surge: ‘We’re not in a great situation’

Government running out of funds for testing, vaccines, treatment.

- By Mike Stobbe

As coronaviru­s infections rise in some parts of the world, experts are watching for a potential new COVID-19 surge in the U.S., and wondering how long it will take to detect.

Despite disease monitoring improvemen­ts over the last two years, they say, some recent developmen­ts don’t bode well:

As more people take rapid COVID-19 tests at home, fewer people are getting the gold-standard tests on which the government relies for case counts.

The Centers for Disease Control and Prevention will soon use fewer labs to look for new variants.

Health officials are increasing­ly focusing on hospital admissions, which rise only after a surge has arrived.

A wastewater surveillan­ce program remains a patchwork that can’t yet be counted on for the data needed to understand coming surges.

White House officials say the government is running out of funds for vaccines, treatments and testing.

“We’re not in a great situation,” said Jennifer Nuzzo, a Brown University pandemic researcher.

Scientists acknowledg­e that the wide availabili­ty of vaccines and treatments puts the nation in a better place than when the pandemic began, and that monitoring has come a long way.

For example, scientists this week touted a 6-month-old program that tests internatio­nal travelers flying into four U.S. airports. Genetic testing of a sample on Dec. 14 turned up a coronaviru­s variant — the descendant of omicron known as BA.2 — seven days earlier than any other reported detection in the U.S.

More good news: U.S. cases, hospitaliz­ations and deaths have been falling for weeks.

But it’s different elsewhere. The World Health Organizati­on

this week reported that the number of new coronaviru­s cases increased two weeks in a row globally, likely because COVID19 prevention measures have been halted in numerous countries and because BA.2 spreads more easily.

Some public health experts aren’t certain what that means for the U.S.

BA.2 accounts for a growing share of U.S. cases, the CDC said — more than one-third nationally and more than half in the Northeast. Small increases in overall case rates have been noted in New York, and in hospital admissions in New England.

Some of the northern U.S. states with the highest rates of BA.2, however, have some of the lowest case rates, noted Katriona Shea of Penn State University.

Dr. James Musser, an infectious disease specialist at Houston Methodist, called the national

case data on BA.2 “murky.” He added: “What we really need is as much real-time data as possible ... to inform decisions.”

Here’s what COVID-19 trackers are looking at and what worries scientists about them.

Test results

Tallies of test results have been at the core of understand­ing coronaviru­s spread from the start, but they have always been flawed.

Initially, only sick people got tested, meaning case counts missed people who had no symptoms or were unable to get swabbed.

Home test kits became widely available last year, and demand took off when the omicron wave hit. But many people who take home tests don’t report results to anyone. Nor do health agencies attempt to gather them.

Mara Aspinall is managing director of an Arizona-based consulting

company that tracks COVID-19 testing trends. She estimates that in January and February, about 8 million to 9 million rapid home tests were being done each day on average — four to six times the number of PCR tests.

Nuzzo said: “The case numbers are not as much a reflection of reality as they once were.”

Hunt for variants

In early 2021, the U.S. was far behind other countries in using genetic tests to look for worrisome virus mutations.

A year ago, the agency signed deals with 10 large labs to do that genomic sequencing. The CDC will be reducing that program to three labs over the next two months.

The weekly volume of sequences performed through the contracts was much higher during the omicron wave in December and January, when more people were getting tested, and already has fallen to about 35,000. By late spring, it will be down to 10,000, although CDC officials say the contracts allow the volume to increase to more than 20,000 if necessary.

The agency also says turnaround time and quality standards have been improved in the new contracts, and that it does not expect the change will hurt its ability to find new variants.

Outside experts expressed concern.

“It’s really quite a substantia­l reduction in our baseline surveillan­ce and intelligen­ce system for tracking what’s out there,” said Bronwyn Macinnis, director of pathogen genomic surveillan­ce at the Broad Institute of MIT and Harvard.

Hospital data

Last month, the CDC outlined a new set of measures for deciding whether to lift mask-wearing rules, focusing less on positive test results and more on hospitals.

Hospital admissions are a lagging indicator, given that a week or more can pass between infection and hospitaliz­ation. But a number of researcher­s believe the change is appropriat­e. They say hospital data is more reliable and more easily interprete­d than case counts.

The lag also is not as long as one might think. Some studies have suggested many people wait to get tested. And when they finally do, the results aren’t always immediate.

Spencer Fox, a University of Texas data scientist who is part of a group that uses hospital and cellphone data to forecast COVID19 for Austin, said “hospital admissions were the better signal” for a surge than test results.

There are concerns, however, about future hospital data.

If the federal government lifts its public health emergency declaratio­n, officials will lose the ability to compel hospitals to report COVID-19 data, a group of former CDC directors recently wrote. They urged Congress to pass a law that will provide enduring authoritie­s “so we will not risk flying blind as health threats emerge.”

 ?? PATRICK ORSAGOS/ASSOCIATED PRESS ?? Ohio State grad student Emily Lu tries to extract RNA from wastewater samples Wednesday to test for fragments of the coronaviru­s. The process of testing the wastewater is not yet reliable enough for data that would help health officials comprehend pending surges of the virus.
PATRICK ORSAGOS/ASSOCIATED PRESS Ohio State grad student Emily Lu tries to extract RNA from wastewater samples Wednesday to test for fragments of the coronaviru­s. The process of testing the wastewater is not yet reliable enough for data that would help health officials comprehend pending surges of the virus.

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