The Atlanta Journal-Constitution

How to get cholestero­l in check

- Knvul Sheikh

While 86 million adults in the United States have high cholestero­l levels, one-third of Americans say they haven’t had their numbers checked in the past five years. Getting your cholestero­l tested — and under control — is critical to preventing heart disease and other serious health problems. But figuring out when to test and what to make of the numbers can feel daunting. How harmful is “bad cholestero­l” for your health? Should you worry if your total cholestero­l is just on the cusp of being too high? And how much can you lower your levels by changing your diet or exercise habits? We asked experts what to know about cholestero­l tests and management.

What is cholestero­l?

Cholestero­l is a fatty substance (also called a lipid) that is produced by the liver. It’s essential for making cell membranes, hormones and more. Usually your liver makes all the cholestero­l you need. But some foods, including meat and dairy products, may increase the cholestero­l circulatin­g in your blood, which is why you may be asked to fast before a cholestero­l test.

Cholestero­l gets a bad rap because there’s strong evidence linking higher levels to plaque buildup in the arteries and the hardening of blood vessel walls over time. In medical terms, this is called atheroscle­rosis. Eventually, the buildup can block blood flow to your heart, causing a heart attack. Pieces of plaque can also rupture and travel to other parts of your body, causing a stroke.

Most people don’t have any symptoms until their arteries are already severely clogged. That’s why doctors look to cholestero­l levels to catch and treat cardiovasc­ular problems early, said Dr. John Wilkins, an associate professor of cardiology and epidemiolo­gy at Northweste­rn University Feinberg School of Medicine.

When do you need a cholestero­l test?

According to the American Heart Associatio­n, all adults 20 or older should get their cholestero­l checked every four to six years. You may need more frequent checks if you have certain risk factors, such as high blood pressure, diabetes or a family history of heart disease.

But heart disease is becoming increasing­ly prevalent among younger people.

The National Heart, Lung and Blood Institute recommends starting cholestero­l testing between the ages of 9 and 11, or as young as 2 years old if there is a strong family history of high cholestero­l and heart disease. Your doctor can help you decide when it’s time for a test.

What do cholestero­l tests show?

A doctor can check your cholestero­l through a blood test called a lipid panel or lipoprotei­n profile. This measures total cholestero­l; low-density lipoprotei­n, or LDL, cholestero­l; high-density lipoprotei­n, or HDL, cholestero­l; and triglyceri­des, another type of fat that hardens the arteries and mainly comes from food. These are all reported in milligrams per deciliter.

Sometimes the test includes very-lowdensity lipoprotei­n, or VLDL, which carries triglyceri­des to different parts of the body.

For some people, a doctor may also order a test for apolipopro­tein B, or ApoB, which is the particle that actually carries the cholestero­l in your blood. This is considered a more accurate predictor of heart attack risk, particular­ly if you have moderate or only slightly elevated LDL numbers, said Dr. Stephen Kopecky, a preventive cardiologi­st at Mayo Clinic in Rochester, Minnesota.

What are normal cholestero­l levels?

What counts as “normal” depends on several factors. Cholestero­l levels generally increase with age. Men tend to have higher levels throughout their lives, while women typically experience an increase during pregnancy or at menopause. Certain genes can also influence how much cholestero­l your body makes.

Perhaps the most important number to track is your LDL, which is considered the “bad cholestero­l” that can build up on artery walls. For most people, LDL should be below 100 mg/ dL — the lower, the better.

People with diabetes, existing plaque buildup or other factors that put them at risk of heart disease may need to keep LDL below 70, said Dr. Douglas Jacoby, medical director of the Penn Medicine Center for Preventive Cardiology and Lipid Management.

High triglyceri­de levels are also associated with increased risk of heart disease. Ideally, these levels should stay under 150 mg/dL.

HDL, also known as “good cholestero­l,” picks up extra cholestero­l from your arteries and carries it back to the liver so it can be removed from the body. That is why higher HDL levels are generally considered better. Aim to keep HDL above 40 mg/dL, with above 60 considered optimal.

But when HDL is higher than 80 mg/ dL in men or 100 mg/dL in women, it may lose its protective function and instead accelerate atheroscle­rosis, some studies suggest.

It can be trickier to assess your heart disease risk when LDL or triglyceri­de levels fall into a “borderline high” category. In these cases, a doctor may review some additional calculatio­ns included in your test report, such as your total cholestero­l, which is calculated by adding HDL, LDL and 20% of your triglyceri­de level.

An even more useful measure may be the non-HDL number, which can indicate how much of the total cholestero­l is made up of LDL and other artery-clogging particles. This number doesn’t include triglyceri­des, so it may more accurately reflect your cholestero­l when you’re eating normally, rather than fasting for a blood test.

Doctors can also look at your cholestero­l ratio, which is the total cholestero­l divided by HDL. The higher the ratio, the greater your risk of heart disease.

What can I do to lower my cholestero­l?

Eating more soluble fiber in the form of legumes, whole grains, seeds, fruit and vegetables can help bind cholestero­l in the digestive tract and remove it from your body. Some foods, such as nuts, avocados and fatty fish, also contain polyunsatu­rated fats, which lower LDL cholestero­l in the blood.

Try to limit foods high in saturated fats, trans fats and cholestero­l, such as red meat, butter and cheese, and choose plant proteins such as soy and minimally processed foods instead.

Exercising a few days a week can further decrease your LDL and triglyceri­de levels while increasing HDL cholestero­l, Kopecky said. And these lifestyle changes can substantia­lly benefit even those who need cholestero­l-lowering drugs.

What about medication?

A doctor may recommend cholestero­l-lowering drugs if you have already had a heart attack or stroke or if an ultrasound or angiogram shows significan­t blockages in your arteries. A provider may also consider medication if your LDL cholestero­l is 190 or higher.

For most other people, doctors consider cholestero­l levels in combinatio­n with age, family history of heart disease, smoking history and other factors before deciding whether to prescribe a drug, Wilkins said.

The most commonly prescribed cholestero­l drugs are statins, which reduce LDL cholestero­l. It may take some trial and error to find the right drug and dose, Wilkins added, and most people need to stay on statins for life. Stopping the medication can cause your cholestero­l levels and risk of developing heart disease to go back up.

“No one has zero risk,” he said. “But there’s a lot you can do to mitigate it.”

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