The Columbus Dispatch

US oil industry fighting sanctions on imports

- By Joshua Goodman and Alexandra Olson

CARACAS, Venezuela — The Trump administra­tion’s decision on Wednesday to slap sanctions on eight members of Venezuela’s all-powerful constituti­onal assembly brings to 30 the number of government loyalists targeted for human rights abuses and violations of democratic norms since anti-government protests began in April.

But even as the list of targeted individual­s grows longer, promised economic sanctions have yet to materializ­e amid an outcry by the U.S. oil industry that a potential ban on petroleum imports from Venezuela — the third-largest supplier to the U.S. — would hurt U.S. jobs and drive up gas costs.

The sanctions announced Wednesday focused on current or former Venezuelan government officials accused by the U.S. of supporting President Nicolas Maduro’s creation of a special assembly charged with rewriting Venezuela’s constituti­on — a move the U.S. says is an attempt by Maduro to shore up his grip on power.

Since its election last month, the 545-member assembly has declared itself superior to all other government institutio­ns and ousted Venezuela’s chief prosecutor, a vocal critic of Maduro.

The U.S. Treasury Department took the unusual step of sanctionin­g Maduro himself last month, freezing any assets he may have in the U.S. and blocking Americans from doing business with him.

The newest additions on Wednesday include Adan Chavez, the older brother of Hugo Chavez, and a national guard colonel lionized by the government after he physically shoved congress President Julio Borges during a heated exchange caught on video.

Venezuela remains highly dependent on oil exports to the U.S. And the prospect of an import ban has alarmed U.S. oil companies.

Nine companies, including Chevron, Valero, Citgo and Phillips 66, currently process Venezuelan crude in more than 20 U.S. refineries, most of them located along the Gulf Coast, according to data from the U.S. Energy Informatio­n Administra­tion.

Scientists have the first major evidence that blood tests called liquid biopsies hold promise for screening people for cancer. Hong Kong doctors tried it for a type of head and neck cancer, and boosted early detection and one measure of survival.

The tests detect DNA that tumors shed into the blood. Some are used now to monitor cancer patients, and many companies are trying to develop versions of these for screening, as possible alternativ­es to mammograms, colonoscop­ies and other such tests. The new study shows this approach can work, at least for this one form of cancer and in a country where it’s common.

“This work is very exciting on the larger scale” because it gives a blueprint for how to make tests for other tumor types such as lung or breast, said Dr. Dennis Lo of Chinese University of Hong Kong. “We are brick by brick putting that technology into place.”

He led the study , published Wednesday by the New England Journal of Medicine. Lo is best known for discoverin­g that fetal DNA can be found in a mom’s blood, which launched a new era of non- invasive testing for pregnant women.

The study involved nasopharyn­geal cancer, which forms at the top of the throat behind the nose. It’s a good test case for DNA screening because it’s an aggressive cancer where early detection matters a lot, and screening could be tried in a population where the cancer is most common — middle-aged Chinese men.

Also, the Epstein- Barr virus is involved in most cases, so tests could hunt for viral DNA that tumors shed into the blood in large quantities, rather than rare bits of cancer cells themselves.

About 20,000 men were screened, and viral DNA was found in 1,112, or 5.5 percent. Of those, 309 also had the DNA on confirmato­ry tests a month later. After endoscope and MRI exams, 34 turned out to have cancer.

More cases were found at the earliest stage — 71 percent versus only 20 percent of a comparison group of men who had been treated for nasopharyn­geal cancer over the previous five years. That’s important because early cases often are cured with radiation alone, but more advanced ones need chemothera­py and treatment is less successful.

Screening also seemed to improve how many survived without worsening disease — 97 percent at three years versus 70 percent of the comparison group.

Only one person who tested negative on screening developed nasopharyn­geal cancer within a year.

The researcher­s estimate 593 people would need to be screened at a total cost of $28,600 to identify one cancer case. It may be worth it in Hong Kong, but maybe not in places like the U.S. where the disease is rare, and more people would have to be screened at a greater cost to find each case, said Dr. Richard Ambinder of Johns Hopkins School of Medicine, who wrote a commentary in the journal.

Still, “this is showing that liquid biopsies have great promise,” he said. “This is an advance that will indeed save lives.”

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