The Columbus Dispatch

Hepatitis A and B vaccines usually don’t require boosters

- DR. KEITH ROACH Dr. Roach answers letters only in his column but provides an order form of available health newsletter­s at www. rbmamall.com. Write him at 628 Virginia Dr., Orlando, Florida, 32853-6475; or ToYourGood­Health@med. cornell.edu.

I have some questions about hepatitis vaccines. I have read recently about an outbreak of hepatitis A in my area.

I went to my hospital and requested the hepatitis A vaccine. I was given the first of a two-shot vaccine, and was told to come back in six months for the second shot. I asked the nurse how long the vaccine would protect me after I took the second shot, and she didn’t know the answer.

My next question involves the hepatitis B vaccine. In 1991, I took the three-shot series of the hepatitis B vaccine. When getting my hepatitis A shot, I asked if my hepatitis B vaccine was still good after 25 years. They drew blood to check titers. A week later, the hospital emailed me and said my titers were low and to come in for a booster shot, which I got.

How come they didn’t just give me the threeshot series again instead of a booster shot? How many years will this hepatitis B booster shot protect me?

Are they working on a vaccine for hepatitis C? A vaccine seems like a good precaution. What do you think?

Hepatitis A vaccine is recommende­d for travelers to areas with high rates of hepatitis A. Two doses are administer­ed, with the second dose given between six and 12 months after the first.

Although we used to tell people that they needed a booster shot 10 years after the completed series, it appears that the protection from the vaccine is longlastin­g, and a booster is not recommende­d.

In an area where there is an outbreak, the Centers for Disease Control and Prevention recommends vaccinatio­n for homeless individual­s; staff and public workers who have close contact with homeless or illicit drug users; and food handlers for adult population­s.

The rate of hepatitis A in the U.S. and Canada is small enough that I think it is not necessary for people with no particular risk factors to get it.

Hepatitis B vaccine is recommende­d for all adults. Ninety-five percent of people will have a good response, as measured by antibody levels in the blood (“titers”). Those with low titers are recommende­d to have a booster. This may relate to people with immune system disease, people with certain DNA factors, people with celiac disease, and if the first vaccine was technicall­y compromise­d.

Fifteen to 25 percent of people who lack adequate titers will get them after one booster dose; 50 percent will after three doses. People who still don’t respond should be tested for having hepatitis B disease. Most people are thought to have lifetime immunity after the vaccine: People with HIV infection and those on dialysis are exceptions.

I have read about progress on a hepatitis C vaccine, which would be a major advance and much more cost-effective than the current treatment, which cures almost all who have hepatitis C but is very expensive.

— D.A.S.

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