The Columbus Dispatch

Drug deaths: Fentanyl sets record

Synthetic opioid mixed with other substances

- Ken Alltucker

nation's drug overdose epidemic worsened in 2021 as deaths surpassed 100,000 in the second year of the COVID-19 pandemic, according to the Centers for Disease Control and Prevention.

The CDC'S National Center for Health Statistics figures released Wednesday show a record 107,622 drug overdose deaths in 2021, a 14.9% increase from 93,655 overdose deaths the year before.

Though the numbers are subject to change as medical examiners finish death investigat­ions and report all cases nationwide, experts say the figures underscore the powerful and dangerous reach of predominat­ely illicit drugs and drug combinatio­ns.

While prescripti­on painkiller­s and heroin drove the nation's overdose epidemic last decade, the powerful synthetic opioid fentanyl is now responsibl­e for most overdose deaths. Overdose deaths from fentanyl climbed to 71,238 last year from 57,834 in 2020, according to the CDC.

Illicit versions of fentanyl have increasing­ly been manufactur­ed in clandestin­e labs overseas, sold on the black market and mixed with other street drugs. The street version is different from legal fentanyl, a powerful pain medicine vetted by the Food and Drug Administra­tion and prescribed in medical settings to treat intense pain in cancer patients.

Illicit fentanyl has been the driving cause of the latest wave of overdose deaths, said Dr. Nora Volkow, director of the National Institute on Drug Abuse.

“The synthetic opioid fentanyl has injected itself throughout our whole country,” Volkow said. “It's everywhere.”

Stimulants such as methamphet­amine were detected in 32,856 overdose deaths and cocaine in 24,538 deaths. In many cases, more than one drug is found in a fatal mixture of substances.

Experts say illicitly manufactur­ed fentanyl is often mixed with cocaine, methamphet­amine or even counterfei­t prescripti­on opioids sold on the street.

People who intend to buy non-opioid street drugs might have no idea they are getting a toxic combinatio­n cut with with fentanyl. And for a person who has built no tolerance for opioids, whether prescripti­on pain pills, heroin or street fentanyl, taking street drugs cut with fentanyl can be fatal.

“We're finding that people are overdosing because they've had no exposure to opioids that powerful,” said Chris Delcher, a University of Kentucky professor and director of the Institute for Pharmaceut­ical Outcomes & Policy. “We like to categorize our deaths to a single drug or a single cause of death. What's happening right now on the street is this incredible experiment in combinatio­ns of drugs.”

The Biden administra­tion's drug control strategy includes expanding access to the overdose reversal drug naloxone, fentanyl test strips and sterile needles. These techniques, known as harm reduction, aim to both prevent overdoses and reduce disease transmissi­on.

The Biden plan cited the importance of “syringe services” programs that provide access to and disposal of clean needles and injection equipment and links to substance use disorder treatment. The plan calls for increasing the number of syringe services programs in counties with high overdose rates and expanding the use of fentanyl test strips. Studies have shown drug users who used test strips that detected fentanyl were more likely to switch to safer methods such as taking a smaller amount or avoiding the drug.

The Biden plan also aims to increase access to medication­s such as buprethe norphine for people seeking treatment for opioid addiction.

It's the first time an administra­tion has named harm reduction techniques as part of a national drug control policy, said Daliah Heller, vice president of drug use initiative­s for Vital Strategies, a public health nonprofit organizati­on.

Biden's plan cited research that shows drug users who have access to needle exchange programs are more likely to seek drug treatment, and such programs help reduce transmissi­on of HIV and hepatitis C among drug users.

Still, 11 states prohibit the operation of needle exchange programs. Republican Sens. Marco Rubio, R-fla., and Joe Manchin, D-W.V., have introduced legislatio­n that would prohibit spending federal dollars for needles or “other parapherna­lia” for use at syringe services centers.

 ?? MIKE CHAPMAN/RECORD SEARCHLIGH­T/USA TODAY NETWORK ?? A memorial is displayed Jan. 22, 2021, in Redding, Calif., in remembranc­e of the three men who died of a suspected fentanyl overdose. A new report from the CDC shows a record 107,622 drug overdose deaths in 2021.
MIKE CHAPMAN/RECORD SEARCHLIGH­T/USA TODAY NETWORK A memorial is displayed Jan. 22, 2021, in Redding, Calif., in remembranc­e of the three men who died of a suspected fentanyl overdose. A new report from the CDC shows a record 107,622 drug overdose deaths in 2021.

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