The Commercial Appeal

TN expects 56K vaccine doses before month’s end

- Brett Kelman Nashville Tennessean USA TODAY NETWORK – TENNESSEE

Tennessee officials expect to receive about 56,000 doses of Pfizer’s coronaviru­s vaccine this month, but this will immunize only a sliver of the residents considered top priority for protection from the virus, according to the state’s revised vaccinatio­n plan.

The state government estimates there are 450,000 people in the highest priority category for vaccinatio­n. This group includes inpatient health care workers, first responders with direct exposure to the public as well as residents and employees of long-term care facilities.

Once this priority group is immunized, the state will vaccinate another 100,000 health care workers with lower levels of exposure, then begin the momentous task of vaccinatin­g about 1.2 million Tennessean­s with two or more medical conditions, like diabetes or hypertensi­on, that make them more vulnerable to the virus.

The revised vaccine distributi­on plan, released Wednesday, aligns the state with new federal recommenda­tions prioritizi­ng distributi­on to health care workers and long-term care facilities. The revised plan contains the first concrete details about the initial shipment of vaccine to Tennessee while simultaneo­usly highlighti­ng the long road ahead. Vaccinatio­ns will stretch deep into the second half of next year, if not beyond.

“Help is on the way. While we still have a ways to go, we all have a role to play,” said Vice President Mike Pence during a Thursday visit to Memphis, where Fedex will be

central vaccine distributi­on. “We all need to continue to practice all those things that protect our health and the health of our families.”

In Nashville, where the outbreak is steadily worsening, public health officials mirrored some of the vice president’s optimism despite a lack of vaccine specifics for the city. Dr. Alex Jahangir, chairman of the city’s coronaviru­s task force, said the forthcomin­g vaccines “gives us hope the beginning of the end is near.”

Dr. Gill Wright, associate medical director for the Nashville Metro Public Health Department, said city officials still didn’t know how much vaccine it would receive or when it would get it.

“We are prepared to get a very small amount to a very large amount and start getting it in people’s arms as soon as we have it,” Wright said.

The Pfizer vaccine will come first. The state government expects to get 58 trays of Pfizer’s two-dose vaccine – each tray contains 975 doses – in mid-december, according to the revised vaccine plan. Fifty-seven trays will be shipped to hospitals to provide the first dose of the vaccine, and one tray will be reserved by the state “in case of spoilage.”

More Pfizer trays are expected in a “second distributi­on” that will provide a second dose to the same people as the first.

The vaccine plan does not say when this second distributi­on is expected, but the two doses are supposed to be given 21 days apart.

Tennessee also expects to receive a smaller shipment of 5,000 doses of the Moderna vaccine, which also requires two doses, “shortly after” the first shipment of Pfizer’s vaccine, according to a news release from the governor’s office. Moderna vaccine will be provided to county health department­s to vaccinate priority population­s.

Neither the Pfizer nor Moderna vaccines are currently approved for distributi­on by the U.S. Food and Drug Administra­tion at this time.

Approval may come later this month when an independen­t FDA committee will meet to review evidence from the Pfizer and Moderna clinical trials on Dec. 10 and Dec. 17, respective­ly.

One member of that committee is Dr. James Hildreth, an infectious disease expert who leads Meharry Medical College in Nashville.

Hildreth said Thursday that, despite the rapid creation of the prospectiv­e vaccines, none of the usual steps taken to verify a vaccine is safe were skipped during developmen­t.

“You need to understand how remarkable this is,” Hildreth said. “It will go down probably as a triumph of big science to develop vaccines in a span of 10 or 11 months.”

Nursing home residents jump to front of the line

Tennessee released its first vaccine distributi­on plan in October, before it was clear what vaccines the state would be getting and when they would be received.

The initial plan establishe­d a fourphase hierarchy for distributi­ng the vaccine, prioritizi­ng health care workers and first responders, then older adults and those with serious comorbidit­ies, then teachers and workers in critical industries, and finally kids and young adults.

The revised plan largely keeps this structure intact but more heavily prioritize­s residents and employees of nursing homes and long-term care facilities.

This population has now moved to the front of the line, jumping ahead of first responders, low-exposure health care workers and people with two or more high-risk comorbidit­ies.

The revised plan also establishe­s a priority hierarchy based on age or health conditions within each individual distributi­on phase.

For example, an emergency room doctor will be prioritize­d over just about anyone else, but if that doctor is above the age of 65, he or she will be prioritize­d over even other doctors.

Brett Kelman can be reached at 615-259-8287 or at brett.kelman@ tennessean.com. Follow him on Twitter at @brettkelma­n.

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