The Day

After study, cancer doctors take chemo off table for some local patients

Women with hormonepos­itive breast tumors but clean lymph nodes don’t need chemothera­py

- By MARTHA SHANAHAN Day Staff Writer

Local doctors treating breast cancer have been able to take chemothera­py off the table for some patients after a study published in The New England Journal of Medicine showed many with early-stage cancer don’t need it.

Scientists tested the cancer in more than 10,000 patients starting in 2016, finding that women with breast cancer that has not yet spread to their lymph nodes and is hormone-positive — fueled by estrogen or progestero­ne — did not benefit from adding chemothera­py to hormone treatments and surgery.

The study, presented last Sunday at an American Society of Clinical Oncology conference in Chicago, refines a commonly used genetic test called Oncotype DX, which estimates the risk that a cancer will recur. The subjects included breast cancer patients both at the Smilow Cancer Hospital Care Center in Waterford and in the Hartford HealthCare hospital system, which includes The William W. Backus Hospital.

It determined that most women whose tumor biopsies fall in a middle range on the test’s 0-100 scale — about 60,000 people a year in the United States — did not benefit from chemo and recovered just as well with only surgery and hormone therapy.

Dr. Kathleen Kurowski, the medical director of the breast health program at Backus, said the breast cancer medical community anxiously had been awaiting the results of the study, which the Associated Press reported was funded by the National Cancer Institute, some foundation­s and proceeds from the U.S. breast cancer postage stamp.

“It really shows that most of them did not benefit from chemothera­py on top of the hormone treatment,” she said.

Chris, a 67-year-old woman who asked to be identified by only her first name because she has been private about her breast cancer diagnosis, underwent a biopsy on the small tumor in her breast last month and learned the results of the genetic test at an appointmen­t with Dr. Jane Kanowitz at the Smilow center on Tuesday.

The tumor biopsy scored a 21 on the genetic test, right in the middle of what until last week was a “gray area” in the spectrum that helps decide

“A week ago I would have discussed with her that there’s a small benefit by adding chemo, and if we wanted to be aggressive and cover every base, it’s a discussion worth having. Today, with that informatio­n being presented ... I was very comfortabl­e saying, ‘Great news, there’s no additional benefit by adding in chemothera­py.’” DR. JANE KANOWICZ, SMILOW CANCER CENTER

New York — A federal judge on Saturday temporaril­y blocked the deportatio­n of a New York pizza shop worker to his native Ecuador after he was arrested while making a delivery to a Brooklyn Army base.

Attorneys for The Legal Aid Society obtained the temporary stay for Pablo Villavicen­cio after a hearing in Manhattan federal court.

The 35-year-old married father of two young girls was arrested on June 1 while making a delivery to the garrison in Fort Hamilton. A routine background check revealed there was a warrant for his arrest for immigratio­n law violations.

Federal Judge Alison Nathan granted the stay until July 20. Villavicen­cio will remain in Immigratio­n and Customs Enforcemen­t custody in New Jersey until his case goes to court.

New York Gov. Andrew Cuomo had asked federal homeland security officials to look into the case, saying recent detentions raise significan­t legal questions.

In a letter to the ICE office in New York, the Democrat said Villavicen­cio’s “expedited removal serves no legitimate public safety purpose and the circumstan­ces leading to his arrest and detention raise serious legal and policy concerns.”

Villavicen­cio’s wife, Sandra Chica, is an American citizen and their daughters, ages 2 and 3, were born in the U.S.

When he arrived at Fort Hamilton, guards requested identifica­tion and he produced a city identifica­tion card. A background check showed that Villavicen­cio had been ordered to leave the United States in 2010, but stayed.

Redmond Haskins, a spokesman for The Legal Aid Society, a not-for-profit organizati­on that provides free services to clients who cannot afford them, said Villavicen­cio has no criminal record.

Haskins said attorneys worked through the night preparing the emergency stay request that was argued in court on Saturday afternoon.

“Although we are disappoint­ed that Pablo will remained detained, today’s stay is a victory for him and his family, and also for due process and the fair administra­tion of justice,” said Gregory Copeland, the supervisin­g attorney of Legal Aid’s Immigratio­n Law Unit. “This decision is also a reminder that the judiciary can still serve as a powerful check when other branches of government make hasty, cruel and reckless decisions.”

The attorneys said they will work with Villavicen­cio to help him secure valid immigratio­n status.

 ?? RICHARD DREW/AP PHOTO ?? New York City Council member Carlos Menchaca, chairman of the council’s Immigratio­n Committee, speaks at a news conference about Ecuadorean restaurant worker Pablo Villavicen­cio, outside the offices of the Immigratio­n and Customs Enforcemen­t, in New...
RICHARD DREW/AP PHOTO New York City Council member Carlos Menchaca, chairman of the council’s Immigratio­n Committee, speaks at a news conference about Ecuadorean restaurant worker Pablo Villavicen­cio, outside the offices of the Immigratio­n and Customs Enforcemen­t, in New...

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