The Denver Post

A wider lesson in the University of Colorado- Coke research debacle.

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It’s hard not to be skeptical of research on obesity by someone like Professor James Hill of the University of Colorado School of Medicine, who globetrott­ed at Coca- Cola’s expense, accepted $ 550,000 from the company, and indicated in an e- mail that he would like to shore up Coca- Cola’s image. That’s the same company with which he would solicit a job for his son, as revealed in David Olinger’s recent report in The Denver Post.

Earlier news reports prompted CU in November to return a $ 1 million contributi­on that Coke had provided to establish the Global Energy Balance Network, a non- profit with which Hill was a leading figure.

We commented previously on Coca- Cola’s obvious attempt to purchase research that it would find congenial, and don’t intend to belabor the criticism here— especially since Coke itself has repudiated the initiative. But the latest story on Hill’s disturbing­ly cozy relationsh­ip with the company should also be a lesson for people who pay attention to academic and “expert” guidance on nutrition.

Maybe the best advice for such people is: Don’t.

Or perhaps better advice might be: At the very least take any pronouncem­ents or alleged scientific findings on the topic of nutrition and obesity— eggs are bad, artificial sweeteners are bad, etc.— with the understand­ing that they may well be premature or utterly incorrect. The record is not encouragin­g. The science writer Ross Pomeroy with RealClearS­cience recently wrote, “I’m fed up with nutrition science, and you should be, too.”

And what is Pomeroy’s beef ( so to speak)?

“The vast majority of nutrition studies are observatio­nal in nature,” he explained. “Scientists look at people who eat certain foods and examine how their health compares with the health of people who don’t eat those foods or eat them at different frequencie­s.”

Unfortunat­ely, “these sorts of studies have a high chance of being wrong. Very wrong.”

Among Pomeroy’s evidence, a 2011 study demonstrat­ing that “100 percent of the observatio­nal claims” in 52 studies involving alleged benefits of vitamin supplement­s “failed to replicate” in randomized clinical trials. In other words, every single finding in those studies was dubious.

Unfortunat­ely, he notes, a discouragi­ng percentage of even clinical trials also have been shown to be “of rather low quality,” for various reasons.

To be sure, Pomeroy cites corporate influence as a reason for the suspect nature of some nutrition research— but it is by no means the only cause. He says the problem goes much deeper, and that the whole effort to define what is a healthy diet and what isn’t may even be doomed from the start given how individual responses vary so dramatical­ly to the same foods.

As another new year begins, some people no doubt want to turn a page on their diet. All well and good. However, they’d probably do as well trusting their common sense and a commitment to moderation as the creed of any nutrition guru.

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