The Denver Post

Painkiller’s maker pulls back.

- By Marley Jay and Matt Perrone

The creator of Oxycontin says it will stop marketing opioid drugs to doctors.

NEW YORK» The maker of the powerful painkiller Oxycontin said it will stop marketing opioid drugs to doctors, bowing to a key demand of lawsuits that blame the company for helping trigger the current drug abuse epidemic.

Oxycontin has long been the world’s top-selling opioid painkiller, bringing in billions in sales for privately-held Purdue, which also sells a newer and longer-lasting opioid drug called Hysingla.

The company announced its surprise reversal on Saturday. Purdue’s statement said it eliminated more than half its sales staff this week and will no longer send sales representa­tives to doctors’ offices to discuss opioid drugs. Its remaining sales staff of about 200 will focus on other medication­s.

The Oxycontin pill, a time-release version of oxycodone, was hailed as a breakthrou­gh treatment for chronic pain when it was approved in late 1995. It worked over 12 hours to maintain a steady level of oxycodone in patients suffering from a wide range of pain ailments. But some users quickly discovered they could get a heroin-like high by crushing the pills and snorting or injecting the entire dose at once. In 2010 Purdue reformulat­ed Oxycontin to make it harder to crush and stopped selling the original form of the drug.

Purdue eventually acknowledg­ed that its promotions exaggerate­d the drug’s safety and minimized the risks of addiction. After federal investigat­ions, the company and three executives pleaded guilty in 2007 and agreed to pay more than $600 million for misleading the public about the risks of Oxycontin. But the drug continued to rack up blockbuste­r sales.

Dr. Andrew Kolodny, director of opioid policy research at Brandeis University and an advocate for stronger regulation of opioid drug companies, said Purdue’s decision is helpful, but that to make a real difference, other opioid drug companies have to do the same.

“It is difficult to promote more cautious prescribin­g to the medical community because opioid manufactur­ers promote opioid use,” he said. Two other companies that sell the medication­s, Johnson & Johnson and Allergan, did not immediatel­y respond to requests for comment.

Kolodny said that opioids are useful for cancer patients who are suffering from severe pain, and for people who only need a pain medication for a few days. But he said the companies have promoted them as a treatment for chronic pain, where they are more harmful and less helpful, because it’s more profitable.

“They are still doing this abroad,” Kolodny added. “They are following the same playbook that they used in the United States.”

Purdue Pharma only does business in the U.S. It is associated with two other companies, Mundipharm­a and Napp, that operate in other countries.

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