The Denver Post

CU study finds imaginatio­n could be as effective as reality

- By Madeline St. Amour

Imagine one of your greatest fears. Now, imagine it again. And again. And again.

After confrontin­g the fear enough times in your head, your mind may stop reacting to it and you could find there’s not much fear left at all, according to a new study from researcher­s at University at Colorado and the Icahn School of Medicine at Mount Sinai in New York that was published in the journal Neuron.

The study found that imagining fears may be just as effective as exposure therapy as facing them head on, according to a news release from CU.

“This research confirms that imaginatio­n is a neurologic­al reality that can impact our brains and bodies in ways that matter for our well-being,” Tor Wager, director of the Cognitive and Affective Neuroscien­ce Laboratory at CU and a senior author on the study, said in a statement.

Clinicians are using the imaginatio­n more and more often as a tool to affect the brain, so the authors of the study say that more research into the area is necessary.

Wager said people should actively manage their imaginatio­ns, as it can be used “constructi­vely to shape what your brain learns from experience.”

About one-third of people in the United States have anxiety disorders, including phobias, according to the release. For decades, clinicians have used exposure therapy — asking patients to face their fears — to treat anxiety and phobia disorders.

In the CU study, researcher­s trained 68 participan­ts to associate a sound with an uncomforta­ble electric shock. The participan­ts were then divided into three groups: some were exposed to the same sound, some were asked to imagine the sound in their heads, and some were asked to imagine pleasant sounds, such as birds and rain. None of the groups experience­d further shocks.

Researcher­s then measured the participan­ts’ responses to the sounds, both real and imagined, in their minds and bodies using skin sensors and functional magnetic resonance imaging, or fMRI.

They found that participan­ts who imagined the threatenin­g sound and the participan­ts who actually heard it had “remarkably similar” brain activity, according to the release. The three parts of the brain that process sound, fear, and risk and aversion all lit up on the fMRI.

After repeated exposure to the sound, whether real or imaginary, those two groups also experience­d “extinction.” This means they lost their fear of the sound. After facing its fear in a safe setting, the brain learned to no longer be afraid — even when it only faced the fear in its imaginatio­n.

The group of participan­ts who imagined pleasant sounds, like birds, had different brain reactions and maintained a fearful response to the threatenin­g sound associated with the electric shocks.

“Statistica­lly, real and imagined exposure to the threat were not different at the whole brain level, and imaginatio­n worked just as well,” said Marianne Cumella Reddan, the lead author of the study and a graduate student in the Department of Psychology and Neuroscien­ce at CU.

There was greater variance in brain activity within the group who imagined the sound, however, Reddan said. This suggests people with more vivid imaginatio­ns might experience greater brain changes when trying to simulate something inside their heads.

Reddan said the new study shows that the imaginatio­n could be even more useful for updating memories than previously believed.

By using the imaginatio­n, people can repackage the memories that cripple them. It can help people change the way they think about memories that aren’t useful, and might stop you from taking on new challenges or make you irrational­ly fearful of certain things.

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