The Denver Post

Cleaning routine shows promise in curbing superbug infection

- By Marilynn Marchione

Think of it as decontamin­ating yourself. Hospitaliz­ed patients who harbor certain superbugs can cut their risk of developing fullblown infections if they swab medicated goo in their nose and use special soap and mouthwash for six months after going home, a study has found.

It’s a low-tech approach to a big problem: About 5 percent of patients have MRSA — antibiotic-resistant Staph bacteria — lurking on their skin or in their noses, putting them at high risk of developing an infection while recovering from an illness or an operation. These can affect the skin, heart, brain, lungs, bones and joints, and most of them land people back in hospitals.

The hygiene steps that researcher­s tested trimmed that risk by nearly one third.

“It’s a very simple solution. You don’t have to swallow a medicine, you just have to clean the outside of your body for a little while longer,” said Dr. Susan Huang of the University of California Irvine School of Medicine. She led the federally funded study, published Wednesday by the New England Journal of Medicine.

A lot has been done to curb infections in hospitals, and attention is shifting to what happens after patients leave. Nine states — California, Washington, Nevada, Minnesota, Illinois, South Carolina, Pennsylvan­ia, Maine and New Jersey — require that hospitals test the most vulnerable patients, such as those in intensive care, for MRSA. Many other places do it voluntaril­y.

The study involved more than 2,000 patients at hospitals in Southern California who were found to carry MRSA, or methicilli­nresistant Staphyloco­ccus aureus bacteria. All were given informatio­n on ways to avoid infection, and half also got special products — mouthwash, liquid soap containing an antiseptic and an antibiotic ointment to swab in the nose. They were told to use these Monday through Friday, every other week for six months.

A year later, 6 percent of those in the deep-clean group had developed an MRSA infection versus 9 percent of the others. They also had fewer infections from other germs. Doctors estimated that 25 to 30 people would need to be treated to prevent one case.

There were no serious side effects; 44 people had dry or irritated skin, and most continued using the products despite that.

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