The Denver Post

Hospitals running out of ICU meds for COVID-19

- By Maria Cheng

Nine leading European university hospitals are warning that they will run out of essential medicines needed for COVID-19 patients in intensive care in less than two weeks as they are increasing­ly crushed by the pandemic.

The European University Hospital Alliance said that without countries cooperatin­g to ensure a steady supply of these drugs, doctors and nurses might no longer be able to provide adequate intensive care for people critically ill with the new coronaviru­s.

In a statement published this week and sent to national government­s, the group said that aside from the need for protective gear and ventilator­s, “the most urgent need now is for the drugs that are necessary for intensive care patients.” They wrote that existing stocks of muscle relaxants, sedatives and painkiller­s were likely to run out in two days at the hardest-hit hospitals, and in two weeks at others.

Last week, Italy’s national pharmaceut­ical agency issued a formal alarm to regional health authoritie­s that the recent jump in demand for some medicines had depleted supplies. The agency set up a special email address for the regional authoritie­s to report any difficulti­es finding certain drugs.

The shortage of such critical medicines has led some hospitals to buy alternativ­e drugs or to try giving patients different dosages.

“It is extremely worrying that overworked and often less-experience­d nurses and doctors-in-training, drafted to fill the gaps, have to use products and dosages that they are not used to,” the group wrote, on behalf of hospitals in Austria, Great Britain, France, Germany, Italy, the Netherland­s, Belgium, Sweden and Spain.

A team of experts for the hospitals authority in Paris last week drew up a list of suggested work-arounds for emergency units to employ to try to ward off what it identified as a “strong risk” of some sedatives and painkiller­s running out. The experts said that for each prescripti­on, medics should ask themselves whether a drug is really necessary and if doses can be reduced, as well as consider alternativ­e drugs.

The European hospital alliance noted that some government­s had reacted to the shortages by refusing to export drugs, and it warned this would prevent drugs from reaching hospitals in dire need of the medicines.

“No single country in Europe has the production facilities to provide all the drugs (or protective gear or ventilator­s) needed,” the group wrote, pointing out that some countries had shut their borders to exporting such drugs but not importing them. “Coordinate­d European action will be of vital importance.”

Last week, the World Health Organizati­on said there were “extreme pressures” at all levels of the medical supply chain, from raw materials to production, distributi­on and delivery.

“The world was not ready for a pandemic, (and) we did not have the stockpiles in place,” said Dr. Mike Ryan, the U.N. health agency’s emergencie­s chief.

Ryan said the WHO was working with other agencies and negotiatin­g with Group of Twenty nations on how to quickly scale up production of essential medical supplies and ensure equitable distributi­on.

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