The Denver Post

Vaccines could be drugmakers’ salvation

- By Jesse Drucker, David Gelles and Katie Thomas

For a long time, drugmakers have been the most hated industry in America. Companies are blamed for gouging prices on lifesaving drugs and enriching themselves through the opioid crisis, among other sins.

Now, with pharmaceut­ical companies racing to find vaccines to end the coronaviru­s pandemic, the industry is hoping to redeem itself in the public’s mind.

The primary goal, of course, is to rescue the world from the grips of a vicious virus. But a big fringe benefit is to get public credit — and to use an improved image to fend off government efforts to more heavily regulate the industry.

Consider Johnson & Johnson, one of the world’s largest health care companies.

In recent years, its reputation has been battered by accusation­s that products such as its artificial hips and talcum powder have harmed customers. In 2019, an Oklahoma judge ordered the company to pay $ 572 million for contributi­ng to the opioid epidemic.

This spring, Johnson & Johnson jumped into the hunt for a COVID- 19 vaccine; its candidate is now in the final stage of clinical trials. ( On Monday, the company said it had temporaril­y paused the study after a

participan­t became sick with an unexplaine­d illness.)

Regardless of whether the vaccine ever comes to market, the company is looking to create a surge of positive publicity from its work. Its chief executive, Alex Gorsky, went on the “Today” show this spring and called Johnson & Johnson’s lab workers heroes. The company has produced a slick, self- promotiona­l online video series, “The Road to a Vaccine,” featuring feel- good interviews with the company’s scientists and segments on issues such as whether it is safe to send children back to school.

Johnson & Johnson’s efforts to develop a vaccine will show that “J& J is a company full of people with heart and soul who are doing this 24/ 7, with all their science and knowhow,” said Dr. Paul Stoffels, the company’s chief scientific officer. While the company’s image at times has been “trashed,” he said, “I hope that we can get to a better reputation.”

That is a widely held sentiment across the pharmaceut­ical industry. Companies are looking for public makeovers as a political battle over drug price controls looms. Others are seizing the once- in- a- generation opportunit­y to raise money for future projects from investors and the government.

For an industry demonized by consumers and politician­s, the hunt for a vaccine “offers a path to redemption,” said J. Stephen Morrison, a senior vice president at the Center for Strategic and Internatio­nal Studies, a think tank in Washington.

Last fall, a Gallup poll found that drugmakers had the worst reputation of any American industry.

When Gallup released the results of this year’s annual survey, conducted in the first half of August, the results confirmed that the pharmaceut­ical industry’s reputation had gotten a bit better. Now, it is second- tolast, having inched past the U. S. government.

Public opinion matters. The industry is facing a fight in Washington over price controls, which could take a bite out of companies’ profits in the United States. The latest salvo came last month when President Donald Trump issued an executive order that called for capping the costs of some prescripti­on drugs.

The industry’s largest trade group, the Pharmaceut­ical Research and Manufactur­ers of America, is fighting back by invoking the industry’s effort to fight the coronaviru­s.

Kim Monk, managing director of Capital Alpha Partners, a policy research firm in Washington, said finding a safe and effective vaccine could help drug companies in their campaign to stave off price controls. “You don’t even need to say it,” she said. “It’s part of the strategy.”

To be sure, the race for a coronaviru­s vaccine is much more than a public relations play. Scientists at pharmaceut­ical companies take great pride in their work to combat human suffering. And there is immense prestige involved in being among the first to successful­ly conquer a devastatin­g global pandemic.

There are also potentiall­y enormous profits on the line.

Vaccines are often thought of as the pharmaceut­ical industry’s sleepy, low- profit backwater, but that is not always the case, said Dr. David Bishai, a professor of health economics at Johns Hopkins University’s school of public health.

Prevnar, a vaccine to prevent pneumococc­al disease, which leads to ear and sinus infections, is Pfizer’s top- selling product, responsibl­e for nearly $ 6 billion in revenue last year.

Merck’s Gardasil, which protects against human papillomav­irus, a sexually transmitte­d disease that can cause cervical cancer, generated close to $ 4 billion in sales last year, making it the company’s thirdbest seller.

While drugmakers generally do not disclose what they earn on individual drugs, two of the world’s largest pharmaceut­ical companies, GlaxoSmith­Kline and Sanofi, have said in securities filings that the profit margins in their vaccine divisions are greater than in their other lines of business.

Ronny Gal, an analyst at Bernstein, estimated that sales from a coronaviru­s vaccine could be up to $ 20 billion in the first year alone. And since diseases are rarely eradicated, vaccines “tend to be a very long- term business,” he said.

Two leading drugmakers have pledged to not profit from their vaccines. But those promises are laden with caveats.

Johnson & Johnson has said it will sell the vaccine on a “not- for- profit” basis for “emergency pandemic use.”

Another major drug company, AstraZenec­a, has made a similar pledge not to profit on its vaccine during the pandemic. But in a contract with one of its manufactur­ers, AstraZenec­a has suggested that it can declare the pandemic to be over as soon as July 2021 — around the time that a successful vaccine is likely to be sold worldwide, according to the Financial Times.

 ?? Erin Schaff, © The New York Times Co. file ?? Pascal Soriot, left, chief executive of AstraZenec­a, and executives from other drugmakers testify at a Senate Finance Committee hearing on drug pricing, on Capitol Hill in Washington, D. C., in 2019.
Erin Schaff, © The New York Times Co. file Pascal Soriot, left, chief executive of AstraZenec­a, and executives from other drugmakers testify at a Senate Finance Committee hearing on drug pricing, on Capitol Hill in Washington, D. C., in 2019.

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