The Guardian (USA)

Chinese Covid-19 vaccine has 86% efficacy, UAE says

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The United Arab Emirates said a Chinese coronaviru­s vaccine tested in the federation of sheikhdoms has 86% efficacy, in a statement that provided few details but marked the first public release of informatio­n on the performanc­e of the shot.

The announceme­nt brought yet another contender into the worldwide race for a vaccine to end the pandemic, a scientific effort in which China and Russia are competing with western firms to develop an effective inoculatio­n.

While questions remain about the shot by the Chinese state-owned pharmaceut­ical firm Sinopharm, already at least one country outside China plans to roll it out in a massvaccin­ation campaign. The UAE conducted a trial beginning in September of the Sinopharm vaccine involving 31,000 volunteers from 125 nations. Volunteers between 18 and 60 years old received two doses of the vaccine over 28 days.

The UAE’s health ministry announced the results via a statement on the state-run WAM news agency on

Wednesday, saying they “have reviewed Sinopharm CNBG’s interim analysis of the phase III trials”.

“The analysis shows no serious safety concerns,” the statement said, without detailing whether any partic

ipant suffered side effects.

It wasn’t immediatel­y clear if the announced results included only those taking part in the testing in the UAE or if they also included results from China and elsewhere. The statement described the vaccine as receiving “official registrati­on” without elaboratin­g on what that meant.

Emirati officials and Sinopharm did not respond to questions from the Associated Press. However, calls to SEHA, the Abu Dhabi health authority, included an option for individual­s to schedule an appointmen­t to receive a “Covid-19 vaccine”. The centre was swamped with calls after the announceme­nt on the vaccine’s efficacy.

The Sinopharm vaccine has been approved for emergency use in a few countries and the company is still conducting late-stage clinical trials in 10 countries. Morocco is gearing up for an ambitious Covid-19 vaccinatio­n programme, aiming to vaccinate 80% of its adults in an operation starting this month that is relying initially on the

Sinopharm vaccine.

Sinopharm’s shot relies on a tested technology, using a killed virus to deliver the vaccine, similar to how polio immunisati­ons are made. Leading western competitor­s, such as the shot made by Pfizer and its German partner BioNTech, use newer, less-proven technology to target the coronaviru­s’s spike protein using RNA. The UK has already begun vaccinatin­g people with the Pfizer shot.

Top officials in the UAE, including Dubai’s ruler, Sheikh Mohammed bin Rashid al-Maktoum, have publicly received the shots as part of the vaccine testing.

Already, Pfizer reports its shot as having 95% efficacy – measuring its performanc­e in controlled conditions – while another RNA candidate from Moderna appears to have 94.5% efficacy. Results suggest a third vaccine from Oxford University and AstraZenec­a is safe and has about 70% efficacy, but questions remain about how well it may help protect those over 55.

In transport, the Pfizer and Moderna vaccines must remain at cold temperatur­es: -70C (-94F) and -20C respective­ly. The Sinopharm vaccine is believed to be able to travel at a temperatur­e of 2-8C, a major draw for areas of the world where nearly 3 billion people live without stable electricit­y and refrigerat­ion. In November, the Communist party secretary for Sinopharm said almost 1 million people in China had received its vaccine.

 ?? Photograph: AFP/ Getty Images ?? The ruler of Dubai, Sheikh Mohammed bin Rashid al-Maktoum, receives the Sinopharm vaccine as part of the UAE trial.
Photograph: AFP/ Getty Images The ruler of Dubai, Sheikh Mohammed bin Rashid al-Maktoum, receives the Sinopharm vaccine as part of the UAE trial.

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