The Guardian (USA)

Possible case of deer-to human Covid infection identified in Canada

- Leyland Cecco in Toronto

Canadian researcher­s believe they have found the first-ever instance of a deer passing the coronaviru­s to a human, warning that broader surveillan­ce of wildlife is needed to prevent further mutations from developing and spreading undetected.

In a paper published last week, but not yet peer reviewed, scientists say at least one case of Covid-19 in humans can be traced to a strain of the virus found in hunted deer.

Biologists have previously found white tail deer population­s infected with Covid in northeaste­rn regions of the United States, as well as central provinces of Canada. While deer aren’t typically seen as a species that can easily pass on the virus to humans, experts had nonetheles­s speculated that transmissi­on was possible.

As part of their study, Canadian scientists took samples from hundreds of white tail deer hunted last fall in southweste­rn Ontario. After conducting nasal swabs and testing the lymph nodes of the deer, they found 17 of the 298 deer were positive for a “new and highly divergent lineage” of the coronaviru­s.

The virus bears little resemblanc­e to strains currently circulatin­g in human population­s. Instead, the closest genetic relative to the strain came fromsample­s taken from humans and mink in Michigan two years ago, tweeted Finlay Maguire, an assistant professor at Dalhousie University and one of the paper’s authors.

The researcher­s then compared the genetic makeup of coronaviru­s found in the deer to cases of the virus found in humans in the region.

The team found one resident who had a strikingly similar strain of the virus and who had been in contact with deer. While the authors said limited sample data made it difficult to fully understand the genetic relationsh­ip between the strains, the timing and location of the infection suggested a deer was the probable source.

Scientists aren’t sure how the deer contracted the virus initially, but further study of the variant circulatin­g in the population suggested that its spike structure meant vaccine escape – the ability for virus to bypass vaccines – was unlikely.

“It’s reassuring that we found no evidence of further transmissi­on, during a time when we were doing a lot of sampling and a lot of sequencing,”

Samira Mubareka, a microbiolo­gist and clinical scientist at Sunnybrook Health Sciences Centre, told CBC News. “If we continue to do this surveillan­ce, we’ll get a much better sense of what the actual risk is.”

Experts have long worried that the virus could infect and then mutate within certain animals, known as reservoir species.

After reviewing the genetic sequence of the virus, Canada’s public health agency said there was no indication it had spread to humans and was probably an “isolated case”.

“Until we know more, people who hunt, trap or work closely with or handle wildlife should take precaution­s to prevent the potential spread of the virus,” the agency said on its website.

 ?? Photograph: Canadian Press/REX/Shuttersto­ck ?? Canadian scientists found a new lineage of the Covid-19 virus in deer hunted last fall in Ontario.
Photograph: Canadian Press/REX/Shuttersto­ck Canadian scientists found a new lineage of the Covid-19 virus in deer hunted last fall in Ontario.

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