The Guardian (USA)

Don’t use weight-loss jabs to counter Christmas indulgence, warn experts

- Nicola Davis Science Correspond­ent

There may be huge pressure to lose weight in the new year after a season of overindulg­ence, but experts have warned against purchasing slimming jabs to shed the festive pounds.

The diabetes drugs have shot to fame after it was found they can help people lose weight by mimicking hormones that make you feel full after eating. But while they have been hailed as an important tool in tackling obesity, their popularity – fuelled by celebrity endorsemen­ts – has also led to concerns.

And slimmers have been warded off buying such jabs in a bid to lose weight in January.

“I think if people are taking these drugs to combat Christmas gluttony then they are going to be disappoint­ed,” said Dr Simon Cork, a senior lecturer in physiology at Anglia Ruskin University. “These drugs are not a quick fix for losing weight but need people to adhere to strict diet and exercise regimes, so taking this drug will not prevent weight gain in those who are overindulg­ing over the Christmas period.”

The drugs are available for free on the NHS, while those who do not meet the criteria can buy them through online pharmacies provided they pass certain checks – and some of them are offering promotions during the winter.

Dr Harshal Deshmukh, a consultant in endocrinol­ogy and diabetes and a senior clinical lecturer at the University of Hull, also urged caution.

“Using appetite suppressan­ts to counter the effects of festive season indulgence in a binge-then-diet approach is ill-advised,” he said.

He added: “Doctors prescribe these medication­s based on specific indication­s, following a thorough evaluation that considers contraindi­cations. Additional­ly, they necessitat­e a gradual titration over time for optimal effectiven­ess, making their haphazard use during the festive season not recommende­d. Moreover, acquiring these medication­s through online pharmacies without a comprehens­ive evaluation is strongly discourage­d.”

The medication, called semaglutid­e, is licensed as Ozempic for managing type 2 diabetes and as Wegovy for weight loss, while a similar drug called liraglutid­e is also available for both purposes.

Cork also raised concerns over access to the medication­s through online pharmacies, with firms showing a “lax attitude” and providing “barely any oversight or clinical management” for patients..

He said: “My concerns are that these drugs are not without side-effects, and whilst severe side-effects are rare they are not absent. The risk of developing significan­t health conditions in people who are obese in general exceeds the risks of side-effects associated with these drugs, but for those that do not meet the clinical criteria for these drugs on the NHS then that risk-benefit-ratio diminishes significan­tly.”

Those who have used such drugs have reported a variety of experience­s, such as debilitati­ng nauseaand an inability to enjoy food.

“The rate[s] of discontinu­ation with these types of drugs are high even when patients are supported and properly prepared for these outcomes.

Moreover, not all people will respond to them,” said Prof Jason Halford, of the University of Leeds, and president of the European Associatio­n for the Study of Obesity. “This makes them anything other than ‘an easy option’.”

Halford added it was also important to carry out due diligence on those selling weight-loss jabs, given reports of fake and potentiall­y dangerous prefilled injection devices.

A Guardian investigat­ion previously revealed some online pharmacies were prescribin­g and dispatchin­g the jabs to people of a healthy weight.

Natasha Devon, a body image and mental health campaigner, added that the drugs did not inspire healthy habits around food.

“In fact, they rather encourage a kind of binge/purge mentality which can be incredibly harmful to both physical and mental health,” she said.

“As someone who suffered from severe bulimia nervosa for several years, I already despair at the way we are urged to ‘compensate’ for festive eating and drinking almost as soon as the bell tolls to mark the beginning of the new year,” she added. “This period of enjoyment shouldn’t be seen as something we have to atone for.”

 ?? ?? The rates of discontinu­ation with the drugs are high even when patients have received proper support, an obesity expert has said. Photograph: Brendan McDermid/Reuters
The rates of discontinu­ation with the drugs are high even when patients have received proper support, an obesity expert has said. Photograph: Brendan McDermid/Reuters

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