The Mercury News Weekend

Sleep disorders linked with preterm birth in new UC San Francisco study

- By Tracy Seipel tseipel@bayarea newsgroup.com Contact Tracy Seipel at 408-920- 5343.

Pregnant women diagnosed with sleep disorders such as sleep apnea and insomnia may be at risk of delivering their babies before reaching full term, according to a UC San Francisco analysis of California births.

The study, published this week in Obstetrics & Gynecology, is reportedly the first to examine the effects of insomnia during pregnancy.

The researcher­s found that the prevalence of pre- term birth — delivery before 37 weeks’ gestation — was 14.6 percent for women diagnosed with a sleep disorder during pregnancy, compared to 10.9 percent for women who were not.

The odds of early preterm birth — before 34 weeks — was more than double for women with sleep apnea and nearly double for women with insomnia.

Complicati­ons are more severe among early preterm births, which the authors said makes this latter finding particular­ly important. So treating sleep dis- orders during pregnancy could be a way to reduce the preterm rate, which is about 10 percent in the United States, more than most other highly developed countries.

The researcher­s focused on 2,265 women with a sleep disorder diagnosis during pregnancy and compared them to the same number who didn’t have that diagnosis, but had identical maternal risk factors for preterm birth, such as a previous preterm birth, smoking during pregnancy, or hypertensi­on.

“This gave us more con- fidence that our finding of an earlier delivery among women with disordered sleep was truly attributab­le to the sleep disorder, and not to other difference­s between women with and without these disorders,” said Jennifer Felder, lead author and a postdoctor­al fellow in the UCSF Department of Psychiatry.

Felder said the significan­ce of the study is that “sleep disorder is a potentiall­y modifiable risk factor.”

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