The Mercury News Weekend

McMath’s parents, doctors both were right

- By Lisa M. Krieger lkrieger@ bayareanew­sgroup.com Contact Lisa M. Krieger at 408- 859- 5306.

In the final act of the fight over Jahi McMath, both her parents and her doctors were proven right.

Yes, she could be sustained. And it was equally true that she’d never, ever get better.

It’s an unsatisfyi­ng coda, reminding us of that hazy line between life and death — and that modern medicine, despite its wonders, remains full of uncertaint­y.

Jahi confounded all prediction­s of a quick demise. Her strong teenage heart, assisted by technologi­es, kept her going far beyond expectatio­ns. She didn’t decompose, as experts predicted. She gave her stunned family the gift of time to gather — and grieve.

But the devastatin­g damage to her brain meant that she remained unconsciou­s, unresponsi­ve and incapable of thought or emotion.

And that damaged brain wasn’t enough to protect her from the ravages of time, all the while tethered to machines. Her family said she died from internal bleeding and kidney issues.

Only an autopsy will resolve the mystery of how much of her brain was damaged when her heart suddenly stopped, then started again, during routine surgery.

It may also reveal whether she was truly capable, as her family asserted, of listening to Golden State Warriors games and voluntaril­y moved her fingers and toes.

Typically, the trauma of the initial injury, called a “sympatheti­c storm,” triggers a massive stress response that f loods the bloodstrea­m with chemicals and damages the hypothalam­us, a small area at the top of the brain stem that regulates body temperatur­e, appetite and the release of important hormones.

There also is normally a cascade of later complicati­ons, like when a computer crashes. The heart, lungs and cellular metabolism go haywire. There is often severe hypertensi­on and imbalances of important regulatory hormones.

But most of our insights come from studies of older patients who donate organs after death — not teenagers. In these older patients, doctors detail dramatic changes that occur soon after brain death, ranging from heart failure to diabetes.

But even the best medical tools cannot replace the brain’s role in regulating the critical balance of essential hormones, immunity and other chemicals, according to Dr. Neal E. Slatkin, a neurologis­t and chief medical officer at San Jose’s Hospice Of The Valley. Ventilator­s apply strong pressure to keep the lungs open and functionin­g, which creates small tears in the lining of the air sacs and bronchial tree, opening up the possibilit­y of infection.

During the vigil, she remained closer to death than she ever was to life.

Yet her heart kept beating. She seemed suspended in time, making it difficult to accept medicine’s now- universal definition of death: loss of brain function.

But without a well-working brain, even that strong heart, the love of her family and the very best of medical technology couldn’t sustain her.

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