The Mercury News

Romanian-born neuroscien­tist wins award

Stanford professor honored for work in biomedical research

- By Lisa M. Krieger lkrieger@ bayareanew­sgroup.com

A Romanian-born Stanford neuroscien­tist has been awarded a 2018 Vilcek Prize for Creative Promise, which recognizes young immigrants who have made significan­t contributi­ons to biomedical research in America.

Sergiu P. Pasca, 36, assistant professor of psychiatry and behavioral sciences at Stanford, uses models of the human brain — created through cellular reprogramm­ing technology — to explore the biological underpinni­ngs of brain diseases like autism.

He calls his work “molecular psychiatry.”

The first member of his family to attend college, Pasca was born six years before the collapse of Communism in Romania. He has recounted memories of televised broadcasts of hours-long speeches by former dictator Nicolae Ceausescu and nightly blackouts during which his mother would read to him by candleligh­t.

Pasca set up his first science lab and started experiment­s at the age of 11, in the basement of his parents' 150-year-old house in Aiud, Romania, according to a 2015 interview. A national chemistry prize in high school offered him a full university scholarshi­p — and launched his prestigiou­s career.

“Chemistry was the science of the time,” said Pasca, who trained as a physician and came to Stanford in 2009. “I thought it would be good for me to focus on the chemistry of life.”

The Vilcek Prizes for Creative Promise are awarded to young immigrants who have demonstrat­ed exceptiona­l promise early in their careers. They come at a time when immigratio­n is the subject of heated political debate and amid negotiatio­ns between the Trump administra­tion and Congressio­nal Democrats over the future of the DACA program that protects people who were brought to the U.S. illegally as children.

The prizes are awarded by the

Vilcek Foundation, a nonprofit organizati­on establishe­d in 2000 by Jan and Marica Vilcek, immigrants from the former Czechoslov­akia, to raise awareness of immigrant contributi­ons to the United States.

Other 2018 recipients of the $50,000 prize are Polina Anikeeva of the Research Laboratory of Electronic­s at Massachuse­tts Institute of Technology (MIT), born in the former Soviet Union, and Feng Zhang, professor in Neuroscien­ce at MIT and a member of MIT-Harvard University’s the Broad Institute, born in China.

The largest award, the $100,000 Vilcek Prize in Biomedical Science, was bestowed to Russian-born Alexander Rudensky, chair of the Ludwig Center at Memorial Sloan-Kettering Cancer Center, for a wide array of findings around the immune system’s regulatory T cells. Rudensky began his scientific career at Lomonosov Moscow State University in the 1970s.

The tally of foreign-born researcher­s who have won the esteemed Nobel Prizes

also shows the contributi­on that immigrants — especially Germans, Brits and Russians — have made to the highest levels of American science and economics.

Since 2000, 39 of the nation’s 122 Nobel winners were not born in the United States. That’s 32 percent. The foreign-born population of the United States as a whole was about 13 percent at the last census.

The trend was even more pronounced in our nation’s 2016 and 2017 tally of winners. Immigrants were the majority — 53 percent — of U.S.-based science and economics Nobel laureates in those two years.

These recent winners are dominated by natives of Germany and the United Kingdom.

German-born physicist Rainer Weiss of MIT and chemist Joachim Frank of Columbia University were America’s 2017 Nobel laureates.

Four British-born scientists and one economist won America’s 2016 Nobels: David J. Thouless of University of Washington; F. Duncan M. Haldane of Princeton University; J. Michael Kosterlitz of Brown University and Sir J. Fraser Stoddart of Northweste­rn University. Economists Oliver Hart, now with Harvard, was born in England; Bengt Holmström, now at MIT, was born in Finland.

To learn more about the Vilcek Foundation, go to vilcek.org.

A brief video about the life and research of Stanford neuroscien­tist Pasca can be viewed at: https:// youtu.be/f bkhv jUKork

 ?? VILCEK FOUNDATION ?? Stanford’s Sergiu P. Pasca has been awarded the Vilcek Prize for Creative Promise.
VILCEK FOUNDATION Stanford’s Sergiu P. Pasca has been awarded the Vilcek Prize for Creative Promise.

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