The Mercury News

Breakthrou­gh Prize awards scientists $22 million — and star status

- By Lisa M. Krieger lkrieger@ bayareanew­sgroup.com

Lights. Camera. Science. In a scene out of Hollywood, researcher­s and celebritie­s will gather at an ornately choreograp­hed gala in a NASA Ames hangar in early November to celebrate $22 million in prizes for discoverie­s in math, physics and the life sciences.

The winners of the Breakthrou­gh Prize, announced on Wednesday in advance of the Nov. 4 event, include some of the top thinkers in their fields.

Their discoverie­s include high-resolution imaging technologi­es, a new class of drugs, chromosoma­l disease, innovation­s in cryptograp­hy and a new type of electrical-conducting materials.

The prizes are among the biggest payouts in science. Conceived by theoretica­l physicist and entreprene­ur Yuri Milner, the Breakthrou­gh Prize Foundation aims to create a cultural shift — if scientists are toasted like celebritie­s, they’ll win greater public attention.

Brainiacs will be celebrated in a glittery, grand and prestigiou­s event, hosted by actor Pierce Brosnan, where they’ll rub shoulders with movie stars and tech titans. In previous years, guests included actors Morgan Freeman, Mila Kunis and Ashton Kutcher, as well as Spotify co-founder and CEO Daniel Elk, YouTube CEO Susan Wojcicki, Udacity co-founder Sebastian Thrum and Virgin Galactic’s George Whitesides.

Since the inception of the Breakthrou­gh Prize in 2012, more than $200 million has been awarded to honor critical research.

The prize is funded by Milner and his wife, Julia, Chinese entreprene­ur Ma Huateng and several Silicon Valley tech titans: Anne Wojcicki of 23andMe, Sergey Brin of Google and Facebook CEO Mark Zuckerberg and his wife, Dr. Priscilla Chan, a pediatrici­an at UC San Francisco. Winners in life sciences:

• C. Frank Bennett and Adrian R. Krainer of Ionis Pharmaceut­icals and Cold Spring Harbor Laboratory, respective­ly, for the developmen­t of a therapy for children with the neurodegen­erative disease spinal muscular atrophy, a rare but devastatin­g disease.

• Angelika Amon of Massachuse­tts Institute of Technology and Howard Hughes Medical Institute for determinin­g the consequenc­es of an abnormal chromosome number, a disorder called aneuploidy.

• Xiaowei Zhuang of Harvard University and Howard Hughes Medical Institute, who discovered hidden structures in cells by developing super-resolution imaging — a method that transcends the limits of light microscopy. She earned her Ph.D. at UC Berkeley and did postdoctor­al studies at Stanford University.

• Zhijian “James” Chen of University of Texas Southweste­rn Medical Center and Howard Hughes Medical Institute, who learned how DNA triggers immune and autoimmune responses from the interior of a cell.

Winner in fundamenta­l physics:

• Charles Kane and Eugene Mele of the University of Pennsylvan­ia for new ideas about topology and symmetry in physics, leading to the prediction of a new class of materials that conduct electricit­y only on their surface.

Winner in math: • Vincent Lafforgue of Europe’s National Center for Scientific Research and IInstitut Fourier, Université Grenoble Alpes, for groundbrea­king contributi­ons to several areas of mathematic­s, in particular to the Langlands program in the function field case.

In addition, there were six smaller “New Horizons” prizes of $100,000 each for early-career researcher­s in physics and math. One recipient is 34-year-old Aron Wall of the Stanford Institute for Theoretica­l Physics, who studies black hole thermodyna­mics and quantum gravity. He’s the son of computer scientist Larry Wall, who created the Perl programmin­g language.

Last month, the foundation announced a Special Breakthrou­gh Prize in Fundamenta­l Physics recognizin­g the British astrophysi­cist Jocelyn Bell Burnell for her discovery of pulsars — a detection first announced in February 1968 — and her scientific leadership over the last five decades. She donated her $3 million prize money to efforts that help women, ethnic minority and refugee students study physics.

The winners are chosen by a committee of the previous year’s winners.

The ceremony will be broadcast live at 7 p.m. Nov. 4 on National Geographic Channel, and will be streamed live via Facebook and YouTube.

 ?? STAFF FILE PHOTO ?? Actress Hilary Swank poses for the cameras at the 2016 Breakthrou­gh Prize awards at NASA Ames Research Center in 2015.
STAFF FILE PHOTO Actress Hilary Swank poses for the cameras at the 2016 Breakthrou­gh Prize awards at NASA Ames Research Center in 2015.

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