Purdue routs No. 2 Ohio State; WSU holds off Oregon

D.J. Knox rushed for 128 yards and three touchdowns, David Blough threw for three more scores, and Purdue shook up the College Football Playoff chase with a 49-20 blowout of No. 2 Ohio State on Saturday in West Lafayette, Ind.

The Boilermakers (4-3, 3-1 Big Ten) won their fourth straight overall, their second in a row over a ranked team and pulled off their biggest upset since taking down then-No. 2 Ohio State 28-23 on Oct. 6, 1984. Purdue also set a school record for points scored against the Buckeyes, besting the previous mark of 41 in 1967.

Mistake-prone Ohio State (71, 4-1) had its 12-game winning streak snapped, fell out of the Big Ten East lead behind rival Michigan and now must fight away its way back into playoff position. NO. 25 WASHINGTON STATE 34, NO. 12 OREGON 20 >> Gardner Minshew threw a 22-yard touchdown pass to Dezmon Patmon in the back of the end zone with 3:40 left and Washington State beat Oregon in Pullman, Wash. The Cougars (6-1, 3-1 Pac-12) won its fourth straight over Oregon (6-1, 3-1). Minshew was 39 of 51 for 323 yards.

NO. 1 ALABAMA 58, TENNESSEE 21 >> Tua Tagovailoa threw touchdown passes to four receivers and Alabama (8-0, 5-0 SEC) started fast again in a victory in Knoxville, Tenn. Alabama had touchdowns on its first four possessions while outscoring Tennessee (3-4, 1-3) 28-0 and outgaining the Volunteers 217-6 in the opening period. NO. 3 CLEMSON 41, NO. 16 NORTH CAROLINA STATE 7 >> Trevor Lawrence threw for a career-high 308 yards, Travis Etienne rushed for three touchdowns, and host Clemson turned an expected ACC showdown into a rout. The Tigers (7-0, 4-0) beat the Wolfpack (5-1, 2-1) for the seventh straight year. NO. 5 LSU 19, NO. 22 MISSISSIPPI STATE 3 >> Michael Divinity Jr.’s interception set up Nick Brossette’s short touchdown run, Cole Tracy kicked four field goals, and LSU won in Baton Rouge, La. LSU’s top linebacker, Devin White, was ejected for targeting in the fourth quarter, meaning he will not be eligible to play in the first half of the Tigers’ upcoming showdown with top-ranked Alabama. NO. 6 MICHIGAN 21, NO. 24 MICHIGAN STATE 7 >> Shea Patterson threw two touchdown passes and Michigan (7-1, 5-0 Big Ten) had a desperately needed victory over Michigan State (4-3, 2-2) in East Lansing, Mich., snapping a streak of 17 consecutive losses to ranked teams on the road. The game was delayed for 1 hour, 15 minutes in the first quarter because of lightning in the area. There was a pregame altercation in the middle of the field where players from both teams exchanged words.

NO. 9 OKLAHOMA 52, TCU 27 >> Kyler Murray threw four touchdown passes in Fort Worth, Texas, Kennedy Brooks and Trey Sermon had 100-yard rushing games with scores, and Oklahoma (6-1, 3-1 Big 12) rebounded from its only loss this season to beat TCU (3-4, 1-3) for the third time in 11 months. NO. 10 UCF 37, EAST CAROLINA 10 >> Darriel Mack Jr. stepped in for Heisman Trophy hopeful McKenzie Milton and rushed for 120 yards and a touchdown, and UCF (7-0, 4-0 AAC) forced five turnovers in beating East Carolina in Greenville, N.C., for its 20th straight victory.

NO. 15 WASHINGTON 27, COLORADO 13>> Jake Browning threw a 26yard touchdown pass to Aaron Fuller on fourth down with less than four minutes remaining, and Washington (6-2, 4-1 Pac-12) held off Colorado (5-2, 2-2) in Seattle. NO. 18 PENN STATE 33, INDIANA

28>> Trace McSorley passed for 220 yards, ran for 107 and had a hand in three touchdowns as Penn State (5-2, 2-2 Big Ten) won in Bloomington, Ind.

TEMPLE 24, NO. 20 CINCINNATI 17 (OT) >> Anthony Russo threw a 25-yard TD pass to Isaiah Wright in overtime for Temple (5-3, 4-0 American) in Philadelphia. Cincinnati (6-1, 2-1) lost its first game. TEXAS TECH 48, KANSAS 16 >> Alan Bowman threw for 408 yards and three touchdowns while playing for the first time since suffering a partially collapsed lung three weeks ago, and Texas Tech beat Kansas in Lubbock, Texas. The true freshman was the nation’s leading passer when he got crushed between two West Virginia defenders on Sept. 29. NEBRASKA 53, MINNESOTA 28 >> Nebraska built a four-TD lead in the first half and pulled away in Lincoln, Neb., giving Scott Frost his long-awaited first win as Cornhuskers coach and ending a program-record 10-game losing streak. UTAH 41, USC 28 >> Tyler Huntley threw for 341 yards and four touchdowns on 22-of-29 passing to lead Utah (5-2, 3-2 Pac-12) over USC (4-3, 3-2) in Salt Lake City.