The Mercury News

Alzheimer’s blood test seems close

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LOS ANGELES » Scientists are closing in on a longsought goal — a blood test to screen people for possible signs of Alzheimer’s disease and other forms of dementia.

On Monday at the Alzheimer’s Associatio­n Internatio­nal Conference, half a dozen research groups gave new results on various experiment­al tests, including one that seems 88% accurate at indicating Alzheimer’s risk.

Doctors are hoping for something to use during routine exams, where most dementia symptoms are evaluated, to gauge who needs more extensive testing. Current tools such as brain scans and spinal fluid tests are too expensive or impractica­l for regular check-ups.

“We need something quicker and dirtier. It doesn’t have to be perfect” to be useful for screening, said Maria Carrillo, the Alzheimer’s Associatio­n’s chief science officer.

Dr. Richard Hodes, director of the National Institute on Aging, called the new results “very promising” and said blood tests soon will be used to choose and monitor people for federally funded studies, though it will take a little longer to establish their value in routine medical care.

“In the past year we’ve seen a dramatic accelerati­on in progress” on these tests, he said. “This has happened at a pace that is far faster than any of us would have expected.”

It can’t come too soon for patients like Tom Doyle, a 66-year-old former university professor from Chicago who has had two spinal fluid tests since developing memory problems four years ago. First he was told he didn’t have Alzheimer’s, then that he did. He finally was diagnosed with different problems.

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