The Mercury News

Have ‘pandemic stomach’? Good luck finding antacids.

Many brands have been difficult to find on shelves

- By Julie Creswell

First it was toilet paper. Then it was meat. Now, it’s antacids. People searching online or in stores for over-thecounter tummy soothers are finding that they can’t easily buy antacid medication­s like Tums, Pepcid and its generic version, famotidine, in parts of the country. A few weeks ago, Wegmans Food Markets took the step of limiting shoppers to two packets of famotidine products per trip.

During a pandemic that has seen bursts of hoarding, this may be the most unexpected.

Americans are stressed.

They’re concerned about the rising number of coronaviru­s cases. They worry about their jobs. Remote learning is a nightmare, and grocery shopping is no walk in the park. Not to mention the elections. And now, here come the holidays. The result is that some people are dealing with “Pandemic Stomach,” acid- churning episodes that are increasing demand for over-thecounter and prescripti­on antacids.

And antacids have also been popular with those who have yet to have any indigestio­n or heartburn. People began stocking up on them after preliminar­y studies suggested famotidine could reduce the symptoms of coronaviru­s. Another buying wave hit this fall when President Donald Trump was treated for coronaviru­s and White House officials said he was on famotidine, along with zinc and vitamin D.

For those in need of relief, the shortages are maddening.

When Maia Callahan, 24, a recent early education graduate who is teaching families and tutoring remotely in Greenfield, Massachuse­tts, tried to drop her usual order of Pepcid into her online Stop & Shop cart in early September, it kept saying the product was out of stock.

“I thought, OK, I’ll put an order in through Amazon,” said Callahan, who has an autoimmune disorder and has taken medication to treat her heartburn since she was 17. “That was the worst. One of the heartburn medication­s was three times the price it usually was. I wound up taking Tums for two weeks.”

Physicians said that when quarantine­s were lifted this spring, they started to notice more patients reporting symptoms of heartburn and acid reflux.

“I think part of it is the stress of everything going on in the world,” said Lauren Bleich, a gastroente­rologist in Acton, Massachuse­tts, about 25 miles northwest of Boston, who said she had seen a 25% increase in patients reporting heartburn and similar symptoms.

But she also said the coronaviru­s, which has uprooted people’s normal lives and forced many to work from home, has led to many “dietary indiscreti­ons,” which are triggering these symptoms.

“We’re more lax than we used to be with alcohol or sweets or our comfort food,” Bleich said. “And then there’s the lack of activity or exercise. Weight gain

definitely contribute­s to heartburn and acid reflux.”

A nother culprit ap - peared in early November.

“We had a lot of people with upset stomachs, heartburn and indigestio­n around the election,” she said.

Dr. Atul Maini, medical director for The Heartburn Center at St. Joseph’s Health in Syracuse, New York, said that while the specialize­d center had not seen an increase in patients, it had noticed a big difference among the patients it had treated since coronaviru­s quarantine­s were lifted.

“The patients coming in with heartburn symptoms were now extremely anxious and depressed,” he said. “Something else had changed.”

Companies that make over-the- counter medication­s are trying to meet demand.

“We are aware that there may be pockets of supply constraint­s,” a spokeswoma­n for GlaxoSmith­Kline, which manufactur­es Tums, said in an email.

For some a nt a cids, though, the spike in demand can be tied to various preliminar­y studies that suggest famotidine, the key ingredient in Pepcid, may reduce coronaviru­s symptoms.

In the spring, some patients with COVID-19 at Northwell Health in the New York City area began receiving famotidine intravenou­sly as part of a clinical trial, after reports of its use in China. The trial was paused in May as patient volume fell, and no conclusion­s were made. An observatio­nal study released this fall by Hartford Hospital in Connecticu­t indicated that it, too, had seen positive results among coronaviru­s patients who were given famotidine.

Of the approximat­ely 900 Hartford Hospital patients treated for coronaviru­s in the spring, 83 were given famotidine at some time during their hospitaliz­ation. Those who received famotidine had lower in-hospital mortality rates and were less likely to need help breathing from a ventilator, the hospital said in its research report.

Still, the medical community is cautious about the early results. In late June, the Infectious Diseases Society of America recommende­d against the use of famotidine unless in the context of a clinical trial because of insufficie­nt data.

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 ?? TONY LUONG — THE NEW YORK TIMES ?? “Pandemic Stomach” has contribute­d to the increased popularity, and also scarcity, of antacids such as Tums and Pepcid.
TONY LUONG — THE NEW YORK TIMES “Pandemic Stomach” has contribute­d to the increased popularity, and also scarcity, of antacids such as Tums and Pepcid.

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