The Mercury News

Will California see another surge of the coronaviru­s?

Some medical experts say they are not expecting a fourth wave of COVID-19 cases

- By Emily DeRuy ederuy@bayareanew­sgroup.com

COVID-19 cases are starting to climb again across much of the U.S., prompting officials to warn of a possible fourth wave of the deadly virus even amid the vaccine rollout. Could California be headed for the same fate?

Infectious disease experts in the Bay Area say the Golden State may be well positioned to escape another surge — but things could change if too many unvaccinat­ed people succumb to the allure of unsafe springtime gatherings.

“I don’t believe we’ll see a rise in California like in other parts of the country,” said George Lemp, an epidemiolo­gist and former director of the HIV/AIDS Research Program at the University of California Office of the President.

There are a few reasons for Lemp’s optimism. The coronaviru­s is spreading slower in California right now than in almost ev

ery other state. He points to a decrease in new cases here across all age groups between the second half of February and the first half of March. Those 65 and older saw cases decline by roughly a third, while those in the 18-34 age group saw slightly more modest declines of about 26%.

“These trends may reflect the early impact of the vaccine distributi­on by age in California,” Lemp said.

Photos of rowdy spring breakers gathering unmasked in places like Miami Beach have prompted warnings to young people from public health officials about the need to continue distancing and other precaution­s. But, Lemp and others said, it’s not clear similar gatherings are happening here, where more stringent coronaviru­s rules remain in place.

Unlike anytime in the past when California has reopened with only mask and distance requiremen­ts and limited capacity at businesses, “we now are applying the protective veneer of vaccines,” said Monica Gandhi, an infectious disease expert at UC San Francisco.

“With roughly 30% of our population in California having received at least one dose of the vaccine and another 30% having some natural immunity,” she said, “we will not see a fourth surge in our state.”

California has its own variant of the original COVID-19 virus, but it appears to also be very susceptibl­e to the vaccines, whereas different variants spreading more rapidly elsewhere in the U.S. may be a little more resistant.

Lemp also thinks the state may be closer to “herd immunity” than people realize — with a majority of the population now likely protected by either vaccines or natural immunity from previous infections. In New York and other places that were hit hard early on, some natural immunity may now be waning. But California was clobbered just a couple of months ago, meaning people who have recovered from the disease may have more robust antibody protection.

And vaccine access and supply are poised to expand rapidly in the coming weeks, Lemp said, so the state may get lucky in escaping a next surge. California­ns 50 and up will be eligible for a shot on Thursday, with those 16 and up gaining access on April 15. The state is expecting to get significan­tly more vaccine in the coming weeks.

It’s clear the race is on. In a call with governors on Tuesday, Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, cited “concerning” national trends: The seven-day average of 65,789 new COVID-19 cases per day is up 19% from two weeks ago. In California, the average is down about 18% over the last two weeks to 2,605 cases.

John Swartzberg, clinical professor emeritus of infectious diseases and vaccinolog­y at UC Berkeley, agrees that California “does have some things going for it that many states do not,” especially in the Bay Area where people tend to follow public health directives and where officials have mandated mask-wearing and other measures.

But, he pointed out, the decline in cases locally is flattening out.

“We are not an island,” he wrote in an email, adding that while Lemp’s calculatio­ns for March “look encouragin­g when compared with a month before, I am not optimistic about the forecast for the next month. I do not think California will have a surge; maybe not a swell. But, I bet the next four weeks will show a net increase.”

Daniel Shin, an infectious disease specialist at El Camino Health who saw one of the first known COVID-19 cases in the Bay Area more than a year ago, is even less optimistic that California’s troubles are behind us. He points out that air travel is up, meaning people from places with more spread and fewer restrictio­ns can bring the virus with them.

“During this entire pandemic, the last 14 months, we have never been excluded from a surge that’s affected other parts of the U.S.,” Shin said. “I am concerned that it’ll eventually catch up to us.”

Shin thinks that while the vaccine rollout has helped mitigate the spread of the disease and contribute­d to a decline in the average age of his hospitaliz­ed patients, he’s worried younger people who aren’t vaccinated yet will get too comfortabl­e with the idea that herd immunity is imminent and engage in risky behavior “that will actually drive the surge.”

In California, hospitaliz­ations among those 80 and older have declined from more than 3,000 at the start of January to fewer than 200 by March 19, dropping markedly each week. While hospitaliz­ations among those 18-29 in the state have fallen, they’ve dropped less significan­tly — from just shy of 700 in the beginning of January to slightly more than 200 in mid-March, holding steady in recent weeks. The week of March 19, hospitaliz­ations among young people outnumbere­d hospitaliz­ations among those 80 and up.

While the numbers in California might not look so worrisome now, Shin thinks people might be in for an unpleasant lesson in exponentia­l growth.

“It doesn’t alarm people when something goes from two to four and four to eight. They just see numbers,” he said. “But for a scientist or epidemiolo­gist, when they see a logarithmi­c rise in numbers, they know it’s eventually going to reach a point where it takes off.”

 ??  ?? Sources: California Department of Public Health, Johns Hopkins University BAY AREA NEWS GROUP
Sources: California Department of Public Health, Johns Hopkins University BAY AREA NEWS GROUP
 ?? MARIO TAMA — GETTY IMAGES ?? Salwa Aziz receives a bandage after a one-shot dose of the Johnson & Johnson COVID-19 vaccine at a Los Angeles clinic targeting immigrants on March 25. Some medical experts say they are not expecting a surge in COVID-19 cases in California.
MARIO TAMA — GETTY IMAGES Salwa Aziz receives a bandage after a one-shot dose of the Johnson & Johnson COVID-19 vaccine at a Los Angeles clinic targeting immigrants on March 25. Some medical experts say they are not expecting a surge in COVID-19 cases in California.
 ?? JOE RAEDLE — GETTY IMAGES ?? Young people gather in a large crowd just before an 8 p.m. spring break curfew goes into effect onMarch 21 in Miami Beach, Florida.
JOE RAEDLE — GETTY IMAGES Young people gather in a large crowd just before an 8 p.m. spring break curfew goes into effect onMarch 21 in Miami Beach, Florida.

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