Jay Leno revives game show ‘You Bet Your Life.’

There are not many questions Jay Leno can’t answer with a joke.

Are there any health protocols when he plays a comedy club? (“Wear a condom.”) Is he vaccinated? (“I got the Pfizer with Moderna drizzle on it and a chocolate almond biscotti — that’s how they do it in Beverly Hills.”)

Leno, 71, remains a gag machine seven years after leaving NBC’s latenight franchise “The Tonight Show,” where he was host for 21 years and No. 1 in the ratings for most of them.

The indefatigable stand-up comic will have a new daily outlet to practice his craft starting Sept. 13 when he fronts an updated version of the classic game show “You Bet Your Life,” nationally syndicated by Fox First Run, a division of Fox Television Stations.

The show’s return comes during a major revival for game shows in recent years. Broadcast TV has been turning to the genre with greater frequency as a cost-effective, low-risk alternative to the expensive scripted programs that viewers now are more likely to seek out on streaming services.

On Leno’s version of “You Bet Your Life,” contestants with different social, cultural and ethnic backgrounds work together in answering questions for cash prizes.

“We’ll pair a rapper from Chicago with an Ohio farmer lady, and they work as a team and it’s quite funny to watch,” Leno said. “There’s no politics, there’s no Trump jokes, there’s no Biden jokes. There are jokes about Congress in that generic sort of ‘they’re idiots’ type of thing.”

Leno will have former “Tonight” bandleader Kevin Eubanks as a sidekick, a role filled by George Fenneman on the original show.

After taping more than 70 episodes, Stephen Brown, executive vice president for programming and development at Fox Television Stations, believes “You Bet Your Life” can provide some relief from these contentious times.