No. 6 Oklahoma routs UCLA

Kyler Murray threw three touchdown passes and ran for two more scores, and No. 6 Oklahoma lost star running back Rodney Anderson to a leg injury in a 49-21 victory over UCLA on Saturday in Norman, Oklahoma.

Anderson ran for 10 yards on the final play of the first quarter, and then got up slowly. He limped off on his own, and trainers tended to the preseason All-Big 12 pick before he headed to the locker room. He was back on the bench later, out of uniform.

NO. 1 ALABAMA 57, ARKANSAS STATE 7: At Tuscaloosa, Ala., Tua Tagovailoa passed for three firstquarter touchdowns and Jalen Hurts added two more before halftime for Alabama.

The Crimson Tide (2-0) racked up big plays on the way to a 40-0 halftime lead while rotating the quarterbacks who battled for the job throughout the offseason. Coach Nick Saban officially announced Tagovailoa would remain the starter Monday, but both were big parts of the plan again.

NO. 3 GEORGIA 41, NO. 24 SOUTH CAROLINA 17: At Columbia, S.C., Jake Fromm threw for 194 yards and a touchdown, all three of Georgia's latest running combo scored touchdowns and the expected Southeastern Conference showdown turned into a blowout.

NO. 4 OHIO STATE 52, RUTGERS 3: At Columbus, Ohio, Dwayne Haskins Jr. threw four touchdown passes and Ohio State rolled to the 900th victory in program history.

Johnnie Dixon grabbed two of Haskins' scoring strikes, and backup quarterback Tate Martell added another touchdown pass and a 47-yard scoring run on a gray, misty afternoon. The Buckeyes, playing in their second game without suspended coach Urban Meyer, piled up 579 offensive yards.

NO. 5 WISCONSIN 45, NEW MEXICO 14: At Madison, Wisc., Jonathan Taylor ran for a career-high 253 yards and three touchdowns, and Wisconsin asserted its dominance after allowing a score on the game-opening drive.

NO. 8 NOTRE DAME 24, BALL STATE 16: At South Bend, Ind., Jalen Elliott had two interceptions that Notre Dame turned into touchdowns and the Fighting Irish held off stubborn Ball State.

The Irish, coming off an emotional 24-17 seasonopening victory over Michigan, looked lackluster against the Mid-American Conference foe. The Cardinals (1-1) also played nothing like the 341⁄2-point underdogs they were labeled in the schools' first meeting in football.

NO. 12 VIRGINIA TECH 62, WILLIAM & MARY 17: At Blacksburg, Va., Steven Peoples had two first-half touchdown runs, and Josh Jackson threw for a touchdown and ran for another for Virginia Tech.

NO. 18 MISSISSIPPI STATE 31, KANSAS STATE 10: At Manhattan, Kan., Nick Fitzgerald returned from a suspension to throw two touchdown passes, Kylin Hill ran for 211 yards and accounted for three scores for Mississippi State.

NO. 21 MICHIGAN 49, WESTERN MICHIGAN 3: At Ann Arbor, Mich., Shea Patterson threw three touchdown passes, one in each of the first three quarters, to help Michigan beat Western Michigan.

NO. 23 OREGON 62, PORTLAND STATE 14: At Eugene, Ore., Justin Herbert threw for 250 yards and four touchdowns for Oregon before heading to the bench in the third quarter.

Herbert was 20 of 26 passes, and had 10 total touchdowns — nine passing and one on the ground — in the Ducks' two opening victories.