The Morning Call

What should the US do with its surplus vaccines?

- By Michael Falcone Michael Falcone is a historian. This story originally appeared in Los Angeles Times.

The United States is making and distributi­ng COVID-19 vaccines so fast that production will soon outstrip demand, leading officials to ask: What should we do with the extra doses?

Most answers have focused on the home front: Dozens of states, including California, are rapidly opening vaccinatio­n eligibilit­y to all adults, and President Joe Biden has doubled the speed of his initial rollout calendar, now calling for 200 million Americans to be vaccinated by the end of April.

While these responses are heartening, there is another way to handle America’s growing stockpile of vaccines, and it draws from a playbook the country used during World War II — give them away.

That’s precisely what America did in the 1940s, when it found itself with an abundance of another new medicine — penicillin. At the time, penicillin was a revolution­ary new drug that could safely cure a slew of previously fatal bacterial diseases.

But it was also considered a strategic war commodity. Having developed and procured the antibiotic specifical­ly for the military and at great public expense, the U.S. government at first hoarded it for exclusive use of Allied troops.

By early 1944, however, U.S. factories led by Merck had ramped up production so fast that Allied needs for the impending D-Day invasion of Normandy were more than fulfilled. Officials then faced the same decision as the Biden administra­tion today: to export or not to export?

Ultimately, war leaders chose to export. In June of that year, the United States shipped the first 10,000 vials of penicillin for civilian use abroad. Just a year later, American firms were sending out tens of billions of units of penicillin-derived

medicines per month. Penicillin went to the Middle East, Central and South America, China and sub-Saharan Africa. It was even sent into Nazi-occupied Norway by the Swedish Red Cross.

This turned out to be a good bet, because exporting penicillin was a boon for both U.S. diplomatic and commercial interests.

Distributi­ng penicillin allowed the U.S. to use its technologi­cal endowments to demonstrat­e global goodwill. The drug was sold commercial­ly where possible, but those who couldn’t pay received it through the Lend-Lease aid program.

It was later sent freely to Europe

through the Marshall Plan. Early on, when shipments were small, recipient countries were relieved to get any penicillin they could, and almost all of them voluntaril­y agreed to the U.S. National Research Council’s regulation­s on use and distributi­on of the drug.

A similar diplomatic reaction would likely occur today. With thousands still dying worldwide of COVID-19 every day and vaccine availabili­ty overwhelmi­ngly concentrat­ed in nations that produce the vaccine, even small shipments to other countries — with firm commitment­s to steady increases — would be better than the status quo.

The Biden administra­tion has taken tentative steps in this direction but must accelerate its efforts. The White House recently announced a plan to share 4 million vaccine doses with Mexico and Canada, but much more is needed: Only 1% of Mexico’s 125 million population has received a shot.

The administra­tion could also start donating doses to COVAX, the United Nations’ global vaccine distributi­on organizati­on. So far, the United States has given COVAX money but not medicine.

The benefits will outweigh the costs in other ways, too. Exporting the COVID-19 vaccine is likely to be good business for the U.S., just as penicillin was. Before World War II, the United States was a bit player in a global pharmaceut­ical sector dominated by European giants. The mass emergency distributi­on of U.S. penicillin changed that.

Through the United Nations Relief and Rehabilita­tion Organizati­on, Americans began a program in 1945 to set up penicillin factories overseas as a form of reconstruc­tion aid. This, combined with sales and donations of U.S.-produced stockpiles, allowed American companies such as Merck and Pfizer to break into foreign markets, forge longterm supply relationsh­ips, expand local licensing arrangemen­ts and transfer production know-how to internatio­nal producers.

Once again we see a lesson for today: The United Nations and others have specifical­ly advocated for transnatio­nal manufactur­ing partnershi­ps and licensing as key ways to vaccinate the world more quickly and fairly.

Widespread rollout of surplus U.S. vaccines would also strengthen internatio­nal ties to American pharma just as competitio­n is on the rise from China, Russia and India. Indeed, China has explicitly tied its global vaccine donation program to its diplomatic image.

America did the same in the 1940s, of course — U.S. officials sent boats through the canals of France showing movies about American aid, and even commission­ed troubadour­s to roam the Sicilian countrysid­e singing songs about a young couple, Giovanni and Mariella, whose romance was saved by penicillin.

Then as now, a pharmaceut­ical giveaway lifts all boats. Such are the potential benefits that U.S. corporatio­ns might even consider doing the donating themselves. Just like today’s Moderna and Johnson & Johnson vaccines, penicillin was developed in an ambitious, federally subsidized crash program.

Corporatio­ns in the 1940s temporaril­y accepted government money and coordinati­on, which put them in a position to continue developing, selling and profiting from antibiotic­s for the rest of the century. The long-term benefits of a giveaway to both U.S. diplomatic power and the U.S. economy might be similarly substantia­l.

But the Biden administra­tion should not wait for private goodwill. The coronaviru­s has tarnished America’s image abroad, since the United States has been the global hot spot for cases and deaths for much of the last year — and ground zero for some of the worst of the COVID-19 era’s science denialism and conspiracy theories.

By donating vaccines to the places that need it most, the U.S. could use its technologi­cal and industrial power to try to undo some of the damage that’s been done to the country’s reputation, as well as create a positive lasting impression for the history books.

Future generation­s might be told that the United States helped the world climb out of the pandemic.

 ?? MORNING CALL FILE PHOTO ?? The Allentown Health Bureau conducts a COVID-19 vaccine clinic Jan. 22 at East Side Youth Center in Allentown.
MORNING CALL FILE PHOTO The Allentown Health Bureau conducts a COVID-19 vaccine clinic Jan. 22 at East Side Youth Center in Allentown.

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