The Morning Journal (Lorain, OH)

Medical research more than just a profit motive

- Keith Roach Contact Dr. Roach at ToYourGood­Health@med. cornell.edu.

DEAR DR. ROACH >> I recently have been diagnosed with Type 2 diabetes. I have read all sorts of pamphlets and brochures; I have been to classes at the local hospital to learn about managing this disease; I have seen the vast array of supplies for testing blood sugar at my local pharmacy. I have come away with a theory on which I would like to hear your opinion.

There is too much money being made in treating and helping folks manage their Type 2 diabetes. A whole industry has been built around this. As a result, there never will be a serious attempt at finding a cure, because as soon as there is a cure, this industry will be out of business and these companies will no longer be able to make a profit. What do you think? — T.B.

DEAR READER >> I hear variations on this theme from time to time, especially about cancer. While I admit that suppressin­g a cure in favor of control would be a successful business model, there are so many different researcher­s from so many different countries, academic institutio­ns and companies that it would be impossible to keep a cure secret.

More importantl­y, the profit motive certainly is a driving force in medical research, but it is by no means the only one. Young and idealistic (and brilliant) researcher­s have made this career choice largely out of an altruistic desire to help. If you’re in it for the money, medical researcher is an unwise choice of occupation.

I wouldn’t discount the scientist’s desire for personal glory, either. Researcher­s dream of being the person to make the key discovery that leads to a cure for this disease, which affects 44 million North Americans and 415 million people worldwide. The payoff for a cure for diabetes likely would be very large, too.

Type 2 diabetes isn’t one single disease, and a cure has been elusive. For now, successful control depends on commitment by the person with diabetes to a healthy diet and exercise (as much as is possible) and by a knowledgea­ble team, including the physicians, nurses, nutritioni­sts, educators and others who help manage this (so far) incurable, but controllab­le, condition.

DEAR DR. ROACH >> I’m a 77-year-old man. My doctor has me on a statin for slightly elevated cholestero­l. He says it’s “insurance,” but I would like to stop taking drugs that may not be necessary. My cholestero­l is 160, triglyceri­des 67, HDL 65, and my blood pressure is 120/80. I have no history of any heart issues. Do you have to taper off a statin, or can you quit cold turkey? — H.C.

DEAR READER >> Even though your cholestero­l numbers and blood pressure are nearly optimal, the risk for a healthy 77-year-old man to have heart disease in the next 10 years is high: 22 percent, according to the most common calculator (at www.cvriskcalc­ulator.com). A statin is likely to reduce that risk, possibly by as much as 5 percent. A statin normally is recommende­d for people with heart disease risk this high. Most experts think that statins work via multiple pathways, not just by lowering cholestero­l.

If you decide to stop, you can stop. However, the rate of heart attack, hospitaliz­ation and heart failure is significan­tly higher in people who stop suddenly or slowly, compared with those who continue, especially in the first six to 12 months.

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