The Morning Journal (Lorain, OH)

Study: DNA websites cas broad net for IDs

About 60percent of the U.S. population with European heritage may be identifiab­le from their DNA by searching websites.

- By Malcolm Ritter

NEW YORK >> About 60 percent of the U.S. population with European heritage may be identifiab­le from their DNA by searching consumer websites, even if they’ve never made their own genetic informatio­n available, a study estimates.

And that number will grow as more and more people upload their DNA profiles to websites that use genetic analysis to find relatives, said the authors of the study released Thursday by the journal Science.

The use of such databases for criminal investigat­ions made headlines in April, when authoritie­s announced they’d used a genetic genealogy website to connect some crime-scene DNA to a man they then accused of being the so-called Golden State Killer, a serial rapist and murderer.

In general, such searches begin on a site by finding a relative linked to a DNA sample. Then sleuths can use other informatio­n like published family trees, public records and lists of survivors in obituaries, plus whatever they know about the person whose DNA began the process. They can build speculativ­e family trees. Eventually, that can point to someone whose DNA is then found to match the original sample.

With DNA databases “you need just a minute fraction of the population to really identify many more people,” said Yaniv Erlich of Columbia University, an author of the study.

Each person in a DNA database acts “as a beacon that illuminate­s hundreds of distant relatives,” said Erlich, who is chief scientific officer of a MyHeritage website.

His paper focused on Americans of European descent because such people are over-represente­d in DNA databases, which makes it easier to find relatives.

The researcher­s started with the 1.28 million participan­ts on the MyHeritage site at the time they did the work. Most had a northern European genetic background. For each, they looked for relatives more distant than first cousins elsewhere in the database.

About 60 percent of the time, they found someone whose genetic similarity was at least equal to that of a third cousin, similar to the degree of relatednes­s that led to the Golden State Killer suspect. Third cousins share great-great-grandparen­ts.

With some basic assumption­s about what kind of data would be available for a criminal suspect, the researcher­s calculated they could pare down the possible identity of the initial person to just 16 or 17 people. That’s limited enough that police could zero in with further investigat­ion, Erlich said.

Erlich and his co-authors suggested such searches could cast a broader net in the near future. A database with DNA profiles of just 2 percent of a population is enough to match nearly everybody with somebody who’s as closely related as a third cousin, researcher­s said. From that, they calculated the genetic profiles of about 3 million Americans of European descent could deliver the equivalent of a third cousin for more than 90 percent of that ethnic grouping.

Websites are getting very close to that, said Erlich, noting MyHeritage has more than 1.75 million participan­ts. He said the website does not allow forensic searches.

Two DNA experts unconnecte­d to the study said third and fourth cousins can both lead to identifica­tions.

“Because the average person has so many of these distant cousins, it becomes reasonably probable that one or more of them is in a publicly searchable database, even if only a small fraction of the U.S. population is included,” Graham Coop and Michael Edge of the University of California, Davis, wrote in a statement to The Associated Press.

“The fact that most suspects could be identified in this way is predictabl­e” from mathematic­al calculatio­ns, and the new paper provides a convincing demonstrat­ion, they said. However, the work raises important policy questions. Should anyone other than law enforcemen­t be allowed to conduct such searches? And under what circumstan­ces should they be permitted?

 ?? RICH PEDRONCELL­I — THE ASSOCIATED PRESS ?? Joseph James DeAngelo, 72, who authoritie­s suspect is the “Golden State Killer” responsibl­e for at least a dozen murders and 50 rapes in the 1970s and 80s, is accompanie­d by Sacramento County Public Defender Diane Howard, right, during his arraignmen­t in Sacramento County Superior Court in Sacramento. Authoritie­s said they used a genetic genealogy website to connect some crimescene DNA to DeAngelo.
RICH PEDRONCELL­I — THE ASSOCIATED PRESS Joseph James DeAngelo, 72, who authoritie­s suspect is the “Golden State Killer” responsibl­e for at least a dozen murders and 50 rapes in the 1970s and 80s, is accompanie­d by Sacramento County Public Defender Diane Howard, right, during his arraignmen­t in Sacramento County Superior Court in Sacramento. Authoritie­s said they used a genetic genealogy website to connect some crimescene DNA to DeAngelo.

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