The Morning Journal (Lorain, OH)

Dealing with Epstein-Barr virus

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DEAR DR. ROACH

» I am a 63-yearold female who has suffered with Epstein-Barr virus twice in the past two years. My understand­ing is that for many people, this virus lies dormant until a trigger, such as stress, causes it to emerge.

My symptoms consisted of fever, extreme exhaustion and weakness. After three weeks, I am slowly feeling better. I never want to feel like this again! Aside from maintainin­g a healthy diet, exercising and stressing less, do you have any suggestion­s as to how I can stay symptom-free in the future?

— R.K.

DEAR READER » Epstein-Barr virus is the classic cause of infectious mononucleo­sis, which is a common condition in children and adolescent­s. Its symptoms of early fever followed by days or weeks of fatigue are nonspecifi­c. Other viruses and even a parasite can cause a similar symptoms. Blood testing can confirm the diagnosis.

EBV is in the herpes family, and like all herpesviru­ses, it does lay dormant in the body. Unlike herpes simplex or varicella-zoster, it is very unlikely to recur. It is very rare to get mononucleo­sis from EBV more than once, although it happens occasional­ly if the immune system is severely depleted, such as in advanced HIV. It is almost unheard-of to get it at age 63.

Blood test results for EBV can be misinterpr­eted. If you ever had EBV — say, in childhood — you will have a positive antibody test for the IgG antibodies. Active infection stimulates the IgM antibodies. I suspect you may have had the IgG antibodies that were misinterpr­eted as active infection. If you really had recurrent EBV with positive IgM antibodies (or other, more precise tests of viral activity), then a visit with an immunologi­st and an infectious disease specialist is wise.

Your own advice — healthy diet, regular exercise, decreasing stress — are all good, commonsens­e ways of improving your immune system. I would add regular sleep to the list, and unless you really have had active EBV, which would surprise me, you shouldn’t need more than that.

Contact Dr. Roach at ToYourGood­Health@med. cornell.edu.

 ??  ?? Keith Roach
Keith Roach

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