The News Herald (Willoughby, OH)

First baby born using deceased’s uterus

- By Maria Cheng The Associated Press

Brazilian doctors are reporting the world’s first baby born to a woman with a uterus transplant­ed from a deceased donor.

LONDON >> Brazilian doctors are reporting the world’s first baby born to a woman with a uterus transplant­ed from a deceased donor.

Eleven previous births have used a transplant­ed womb but from a living donor, usually a relative or friend.

Experts said using uteruses from women who have died could make more transplant­s possible. Ten previous attempts using deceased donors in the Czech Republic, Turkey and the U.S. have failed.

The baby girl was delivered last December by a woman born without a uterus because of a rare syndrome. The woman — a 32-year-old psychologi­st — was initially apprehensi­ve about the transplant, said Dr. Dani Ejzenberg, the transplant team’s lead doctor at the University of Sao Paulo School of Medicine.

“This was the most important thing in her life,” he said. “Now she comes in to show us the baby and she is so happy,”

The woman became pregnant through in vitro fertilizat­ion seven months after the transplant. The donor was a 45-year-old woman who had three children and died of a stroke.

The recipient, who was not identified, gave birth by cesarean section. Doctors also removed the womb,

partly so the woman would no longer have to take antireject­ion medicines. Nearly

a year later, mother and baby are both healthy.

Two more transplant­s are planned as part of the Brazilian study. Details of the first case were published Tuesday in the medical journal Lancet.

Uterus transplant­ation was pioneered by Swedish doctor Mats Brannstrom, who has delivered eight children from women who got wombs from family members or friends. Two babies have been born at Baylor University Medical Center in Texas and one in Serbia, also from transplant­s from living donors.

In 2016, doctors at the Cleveland Clinic transplant­ed a uterus from a deceased donor, but it failed after an infection developed.

“The Brazilian group has proven that using deceased donors is a viable option,” said the clinic’s Dr. Tommaso Falcone, who was involved in the Ohio case. “It may give us a bigger supply of organs than we thought were possible.”

The Cleveland program is continuing to use deceased donors. Falcone said the fact that the transplant was successful after the uterus was preserved in ice for nearly eight hours demonstrat­ed how resilient the uterus is. Doctors try to keep the time an organ is without blood flow to a minimum.

Other experts said the knowledge gained from such procedures might also solve some lingering mysteries about pregnancie­s.

 ?? COURTESY DR. WELLINGTON ANDRAUS VIA AP ?? This shows the baby girl born to a woman with a uterus transplant­ed from a deceased donor at the Hospital das Clinicas of the University of Sao Paulo School of Medicine, Sao Paulo, Brazil, on the day of her birth. Nearly a year later, mother and baby are both healthy.
COURTESY DR. WELLINGTON ANDRAUS VIA AP This shows the baby girl born to a woman with a uterus transplant­ed from a deceased donor at the Hospital das Clinicas of the University of Sao Paulo School of Medicine, Sao Paulo, Brazil, on the day of her birth. Nearly a year later, mother and baby are both healthy.

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