The News-Times

Doctor won’t prescribe treatment

- Keith Roach, M.D. Readers may email questions to: ToYourGood­Health@med .cornell.edu or mail questions to 628 Virginia Dr., Orlando, FL 32803.

Dear Dr. Roach: After suffering from menopausal symptoms starting at age 42, I was finally prescribed HRT at age 57. What relief I had, as it was the only remedy to alleviate my hot flashes, weight gain, lack of sleep and vaginal dryness.

Once I hit 60, I was ordered to stop the HRT, and no one since will prescribe it for me now. I am 66 now, suffer daily with hot flashes and have my sleep interrupte­d at least five times a night with terrible night sweats. I have tried just about every over-the-counter offering with zero effectiven­ess.

I will gladly trade the greater risk of heart attack and stroke, and the possible shorter life span, for relief from symptoms that affect my daily quality of life. If I had a choice, I would ask for continued prescripti­ons of HRT to give me relief. Why don’t I have that choice as a patient?

Answer: A patient always has the right to refuse a treatment recommende­d from a physician. However, the physician has the obligation to consider the risks and benefits of a treatment and is not obliged to prescribe a treatment they do not think is appropriat­e.

If a patient asks me for a treatment that has been shown not to be effective and has the potential for serious adverse effects, I don’t prescribe it, but will work with the patient to find alternativ­e treatments. For example, some non-hormonal prescripti­on treatments are moderately effective for hot flashes and sleep disturbanc­e, and topical estrogen is very effective for vaginal dryness.

However, the case of hormone replacemen­t therapy for symptoms of menopause is more complicate­d, because estrogen is the most effective treatment we have for menopausal symptoms, particular­ly for hot flashes. There are risks to hormone therapy, but the benefits for some women are so great that they are willing to accept some risk of treatment.

You mentioned the risk of heart disease and stroke. A landmark study, the Women’s Health Initiative, helped to define and quantify those (and other) risks. Its effect has been to dramatical­ly reduce the prescribin­g of menopausal hormone therapy, but the results should not be interprete­d to mean that hormone treatment is always inappropri­ate, even with women in their mid-60s where risks are higher.

Moreover, a woman’s entire health status should be considered when deciding whether to prescribe hormone treatments. In women with a history of an estrogende­pendent tumor (like many breast cancers), a history of a blood clot or a stroke, or a few other issues, the harms almost certainly outweigh the benefits. Otherwise, a wise clinician looks at the patient’s risk for heart disease, blood clots and other conditions.

Women at a very high risk for heart disease should probably avoid estrogen; otherwise, using lower-dose estrogen by patch (rather than pill) is wise for women at moderate risk, such as those in their 60s.

Physicians do not want to prescribe medication­s that will harm their patients, and most have stopped prescribin­g menopausal hormone therapy entirely for women, to prevent disease. However, it still has a role in treating symptoms. I recommend you seek out an expert in treatment of menopausal treatments in order to have a better quality of life.

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