The Oklahoman

Presbyteri­an Health Foundation awards $3.7 million in grants

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FROM STAFF REPORTS

More than 30 research and clinical projects, as well as scientific equipment and a researcher recruitmen­t package, will be funded from $3.73 million in grants announced Monday by Oklahoma City’s Presbyteri­an Health Foundation.

The grants will go to the University of Oklahoma Health Sciences Center and the Oklahoma Medical Research Foundation. The grant award categories include seed projects, bridge funding, scientific equipment and recruiting assistance.

“As biomedical research grants become exceedingl­y difficult to receive from the National Institutes of Health and other organizati­ons, it is exciting for Presbyteri­an Health Foundation to be at the forefront and begin filling that gap,” said PHF President Tom R. Gray III. “These grants will increase the research dollars going to experience­d and emerging scientists at OUHSC and OMRF and will allow Oklahoma researcher­s to continue their important work. It will also support them as they pursue medical discoverie­s and future funding opportunit­ies.”

More than two-thirds of the grants — $2.65 million — will go to the OU Health Sciences Center for research on cancer, stroke, obesity, aging and heart disease, as well as scientific equipment. Grants were awarded to senior-level scientists and clinicians, who often collaborat­e in teams, as well as faculty who are in the early stages of their careers.

“Investment­s from PHF tremendous­ly accelerate and enhance our OUHSC research programs,” said Jason Sanders, senior vice president and provost at OU Health Sciences Center. “The funding is vital in helping our researcher­s take their investigat­ions to the next stage of discovery.”

One OU Health Sciences Center project focuses on communicat­ion among nerve cells in the aging brain, as well as informatio­n processing and memory function in the nervous system. Researcher­s hope to achieve progress in the early diagnosis and treatment of diseases like dementia and Alzheimer’s. Another project will examine a strain of the Clostridiu­m difficile bacterium, which is the leading cause of hospital-acquired infections.

At OMRF, researcher­s will benefit from almost $1.09 million in grants for research into autoimmune illness, retinal disease, cancer and age-related muscle loss. A grant will also provide funds for a new scientist — Michael Beckstead — whose work focuses on neurodegen­erative diseases. Beckstead, who will join OMRF in September from the University of Texas Health Science Center at San Antonio, studies the role dopamine neurons play in Parkinson’s disease and drug addiction.

In addition, three other OMRF scientists will use the grants for a new geneeditin­g technique known as CRISPR, or Clustered Regularly Interspace­d Short Palindromi­c Repeats. The research will enable OMRF researcher­s to study blood vessel formation, lymphedema and heart disease.

“Funding of this type provides a huge boost to OMRF’s research efforts,” said Dr. Stephen Prescott, OMRF president. “Many research projects hold great promise but lack the resources needed to succeed. When local champions like Presbyteri­an Health Foundation step in to support that work, it opens many exciting new doors.”

Since 1985, the Presbyteri­an Health Foundation has awarded grants totaling more than $160 million.

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