The Oklahoman

Scientists successful­ly clone monkeys; are humans up next?

- BY MALCOLM RITTER The Associated Press

NEW YORK — For the first time, researcher­s have used the cloning technique that produced Dolly the sheep to create healthy monkeys, bringing science an important step closer to being able to do the same with humans.

Since Dolly’s birth in 1996, scientists have cloned nearly two dozen kinds of mammals, including dogs, cats, pigs, cows and polo ponies, and have also created human embryos with this method. But until now, they have been unable to make babies this way in primates, the category that includes monkeys, apes and people.

“The barrier of cloning primate species is now overcome,” declared Muming Poo of the Chinese Academy of Sciences in Shanghai.

In a paper released Wednesday by the journal Cell, he and his colleagues announced that they successful­ly created two macaques. The female baby monkeys, about 7 and 8 weeks old, are named Zhong Zhong and Hua Hua.

“It’s been a long road,” said one scientist who tried and failed to make monkeys and was not involved in the new research, Shoukhrat Mitalipov of Oregon Health & Science University. “Finally, they did it.”

Poo said the feat shows that the cloning of humans is theoretica­lly possible. But he said his team has no intention of doing that. Mainstream scientists generally oppose making human babies by cloning, and Poo said society would ban it for ethical reasons.

Instead, he said, the goal is to create lots of geneticall­y identical monkeys for use in medical research, where they would be particular­ly valuable because they are more like humans than other lab animals such as mice or rats.

The process is still very inefficien­t — it took 127 eggs to get the two babies — and so far it has succeeded only by starting with a monkey fetus. The scientists failed to produce healthy babies from an adult monkey, though they are still trying and are awaiting the outcome of some pregnancie­s. Dolly caused a sensation because she was the first mammal cloned from an adult.

 ?? [AP PHOTO] ?? In this undated photo provided by the Chinese Academy of Sciences, cloned monkeys Zhong Zhong and Hua Hua sit together with a fabric toy.
[AP PHOTO] In this undated photo provided by the Chinese Academy of Sciences, cloned monkeys Zhong Zhong and Hua Hua sit together with a fabric toy.

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