The Oklahoman

Ideas for monitoring medical marijuana

- BY LAWRENCE PASTERNACK Pasternack is a philosophy professor at Oklahoma State University. Senate Bill 1120 has been passed by the state Senate and now goes to the House.

As of January, 20 states have legalized medical but not recreation­al marijuana, and nine states (plus Washington, D.C.) have further legalized it for recreation­al purposes. Insofar as we can use these states to predict the consequenc­es of State Question 788, let me offer a few details and suggestion­s.

First, according to the Journal of the Society for Prevention Research, states that have approved medical marijuana did not see a rise in marijuana consump- tion among teens and adults 12-25. Why is that? Most high school and college students know, by word of mouth, where to buy marijuana. By contrast, adults 26 and older have far less access and tend to be more risk averse. Hence, there is an average rise in use from 5.1 percent to 6.5 percent among adults 26 and older in medical marijuana states, which is roughly on par with their medical marijuana enrollment statistics: Arizona (1.7 percent), Connecticu­t (0.7), Hawaii (1.4), Montana (2.1), etc.

Neverthele­ss, this doesn’t mean that our legislator­s should simply let SQ 788 pass without enacting any controls. Given that proponents of SQ 788 base their arguments on marijuana’s medical benefits, they should be willing to support legislativ­e action that more carefully distinguis­hes between legitimate medical use versus pretexts for recreation­al use. The challenge is in finding the right way to do this.

The approach taken by Senate Bill 1120 is to list specific medical conditions such as neuropathi­c pain, multiple sclerosis based spasticity, and nausea from chemothera­py. The difficulty with this is three-fold. First, it does not fully cohere with the findings of current research (e.g. Crohn’s disease, fibromyalg­ia). Second, it does not provide for the results of emerging research (e.g. rheumatoid arthritis, ALS). Third, it has our government interferin­g in our medical treatment. While it is appropriat­e for legislator­s to set standards for safety and efficacy, they should allow medical science, the judgment of physicians and the needs of patients to determine care.

Accordingl­y, I have three recommenda­tions. First, let medical science and not our politician­s tell us what marijuana is good for. Have SB 1120 define a “qualifying condition” as “a painful or debilitati­ng medical condition for which there have been controlled, randomized studies published in peer-reviewed medical journals with an impact factor of 2.0 or greater, showing an improvemen­t in symptoms of at least 20 percent, with a p-value of .05 or better.” Second, SB 1120 is unclear about the difference between vaporizing vs. smoking marijuana. Vaporizing gassifies rather than burns (combusts) the material. Further, vaporizing is a more medically appropriat­e route of administra­tion versus oral ingestion. Not only will it relieve pain, nausea, etc. far more quickly, but also, because CBD has very low oral bioavailab­ility, eating marijuana tends to accentuate THC’s effects, including anxiety, paranoia and even hallucinat­ions.

Third, over the past decade, considerab­le effort has gone into developing strains with specific CBD:THC ratios. Because CBD counteract­s the psychotrop­ic effects of THC, strains with high CBD to THC ratios offer commensura­te medical benefits while limiting its recreation­al appeal. Some of these strains include: “Avidekel” with a CBD:THC ratio of 15:1, “Lilly CBD” (3:1), and “Harlequin” (5:2). Given that the existing black market trade in marijuana has CBD to THC ratios much more conducive to recreation­al use, by limiting sales and cultivatio­n to only those strains with high CBD to THC ratios, there will be much less misuse and reason for diversion.

 ??  ?? Lawrence Pasternack
Lawrence Pasternack

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