The Oklahoman

Why is Google killing off Fresno’s mosquitoes?

- BY KRISTEN V BROWN Bloomberg

Silicon Valley researcher­s are attacking flying bloodsucke­rs in California’s Fresno County. It’s the first salvo in an unlikely war for Google parent Alphabet Inc.: eradicatin­g mosquito-borne diseases around the world.

A white high-top Mercedes van winds its way through the suburban sprawl and strip malls as a swarm of male Aedes aegypti mosquitoes shoot out of a black plastic tube on the passenger-side window. These pests are tiny and, with a wingspan of just a few millimeter­s, all but invisible.

“You hear that little beating sound?” says Kathleen Parkes, a spokespers­on for Verily Life Sciences, a unit of Alphabet. She’s trailing the van in her car, the windows down. “Like a duh-duh-duh? That’s the release of the mosquitoes.”

Jacob Crawford, a Verily senior scientist riding with Parkes, begins describing a mosquito-control technique with dazzling potential. These particular vermin, he explains, were bred in the ultra-high-tech surroundin­gs of Verily’s automated mosquito rearing system, 200 miles away in South San Francisco. They were infected with Wolbachia, a common bacterium. When those 80,000 lab-bred Wolbachia-infected, male mosquitoes mate with their counterpar­t females in the wild, the result is stealth annihilati­on: the offspring never hatch. Better make that 79,999. “One just hit the windshield,” says Crawford.

Mosquito-borne disease eradicatio­n is serious stuff for Alphabet, though it is just one of many of the company’s forays into health care and life sciences. Through Verily and other branches of the company, Alphabet is investigat­ing smart contact lenses, artificial intelligen­ce applicatio­ns for health care, and the molecular mechanisms of aging. Just this month, Alphabet hired Geisinger Health CEO David Feinberg to oversee its many healthcare initiative­s.

Verily guards its technology closely. But it stands to reason that if it succeeds in making mosquito control easy and cheap enough, it could have a lucrative offering on its hands: Many government­s and businesses around the globe might be glad to pay for a solution to their mosquito problems.

In the arid climate of California’s Central Valley, A. aegypti are detested for their vicious bite. But there, at least, they don’t typically transmit disease. Other places aren’t so lucky. The mosquito species is among the world’s deadliest, spreading diseases such as dengue fever and chikunguny­a in the tropics and subtropics. The diseases its bite carries kill tens of thousands of people every year and infects millions more. Releasing Wolbachia-infected mosquitoes into the wild may eventually wipe out entire population­s of deadly mosquitoes and the diseases they carry.

At least that’s the plan if the field tests pan out in California. Every morning during mosquito season which runs from April to November-the van, emblazoned with “Debug Fresno,” cruises through leafy housing tracks full of multistory homes. At predetermi­ned locations, an algorithm automatica­lly releases carefully calculated numbers of mosquitoes, counting each individual insect with the help of a laser as it exits the van.

 ?? [AP PHOTO] ?? A mosquito factory is shown at Verily Life Sciences’ lab in South San Francisco.
[AP PHOTO] A mosquito factory is shown at Verily Life Sciences’ lab in South San Francisco.

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