The Oklahoman

Biden urged to change vaccine plan

Democratic lawmaker wants to get more doses out to Americans

- Nicholas Wu Contributi­ng: Michael James, Ryan Miller and Grace Hauck

WASHINGTON – Rep. Ro Khanna, D-Calif., entered the debate over giving the COVID-19 vaccines as a single dose and delaying a second dose, urging President Joe Biden’s administra­tion to consider a new vaccine strategy to get more doses out to Americans.

In a letter sent Wednesday to Centers for Disease Control and Prevention Director Rochelle Walensky and COVID-19 task force coordinato­r Jeffrey Zients, Khanna urged them to work with the Advisory Committee on Immunizati­on Practices, a CDC committee, “to gather and consider data” on the effectiveness of single-dose vaccinatio­ns. Khanna is the first lawmaker to publicly call on the Biden administra­tion to consider the strategy in hopes of sparking a debate on the question amid a bumpy vaccine rollout.

“Every personwe vaccinate today is a life potentiall­y saved. If clinical data supports an effective one-dose vaccine regimen, it could nearly double our daily vaccinatio­n numbers, simplify administra­tion, and reduce COVID-19 deaths in the long run,” he wrote.

Khanna’s position is in contrast with that of the Biden administra­tion, which has supported delivering both doses of the vaccine within the recommende­d time frame of 28 days for the Moderna/BioNTech vaccine and 21 days for the Pfizer vaccine.

Some medical experts have advocated giving the Moderna and Pfizer/BioNTech vaccine in single-dose regimens rather than the currently recommende­d two doses to rapidly build immunity among Americans.

“We still want to get two doses in everyone, but I think right now, in advance of this surge, we need to get as many one-doses in as many people over 65 as we possibly can, to reduce serious illness and death that is going to occur over the weeks ahead,” said Michael Osterholm, an epidemiolo­gist who advised the Biden transition team, on Sunday’s “Meet the Press,” referring to a potential surge in cases as newCOVID-19 variants spread.

And Robert Wachter, chair of the department of medicine at the University of California-San Francisco, and Ashish Jha, dean of the Brown University

School of Public Health, wrote in a Jan. 3Washingto­n Post op-ed, “We should give people a single vaccinatio­n now and defer their second shot until more doses of vaccine become available” because of vaccine supply constraint­s.

Biden administra­tion officials said Monday that they were not planning on changing their strategy to administer two doses of the vaccine.

Walensky, the CDC director, told reporters “we should follow the science” in deploying the vaccines and noted there was an “ongoing concern that we would see the emergence of more variants if therewas low-level virus and it was allowed to mutate.”

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, reiterated the current policy about getting two doseswhen“dealing with a two-dose regimen” like Pfizer/BioNTech and Moderna’s, saying “the first priority will always be to get the people who have gotten their first doses to get their second doses. And then additional doses will be given to the next group of people who will get their first doses.”

“There are no doses that are hanging around,” he said. “A dose that is available is going to go into someone’s arm.”

Khanna told USA TODAY in a phone interview he wanted the CDC to consider the change because of a potential “five-alarm fire” the country faced with another surge in COVID-19 cases.

The countrywil­l “have tomake decisions about saving lives” and needed a “data-driven approach,” he said. Khanna acknowledg­ed some concerns about a possible false sense of security among people who received a single dose but argued that given the severity of the pandemic, “people are not going to be lulled into complacenc­y” or be confused about a second dose.

Asked about the Biden administra­tion’s stance and concerns about a single dose not protecting against mutations, Khanna said “let’s get the data out there,” adding it was a question that should be discussed openly. The Centers for Disease Control and Prevention updated its vaccine guidance at the end of January to say the second dose of a two-shot vaccine can be administer­ed up to six weeks after the first.

The mRNA COVID-19 vaccines developed by Pfizer/ BioNTech and Moderna require two doses, given three weeks and one month apart, respective­ly. But second shots can still be administer­ed beyond that time frame, up to 42 days after the first, the CDC said late lastweek. There’s no data on doses administer­ed after that time.

The agency also said a person may receive a different vaccine for the second shot only in “exceptiona­l situations” where the first-dose vaccine is unknown or unavailabl­e. Clinical trials did not evaluate the safety or effectiveness of interchang­ing vaccines.

Some medical experts have advocated giving the Moderna and Pfizer/BioNTech vaccine in single-dose regimens rather than the currently recommende­d two doses.

 ?? ANDREW HARNIK/AP ?? Rep. Ro Khanna, D-Calif., is the first lawmaker to publicly call on the administra­tion to consider the strategy in hopes of sparking a debate amid a bumpy vaccine rollout.
ANDREW HARNIK/AP Rep. Ro Khanna, D-Calif., is the first lawmaker to publicly call on the administra­tion to consider the strategy in hopes of sparking a debate amid a bumpy vaccine rollout.

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