The Oklahoman

Weight Watchers set to add anti-obesity drugs

Company gets into meds with startup purchase

- Karen Weintraub Health and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competitio­n in Healthcare. The Masimo Foundation does not provide editorial input.

WeightWatc­hers – for more than 60 years the standard bearer of diet and exercise programs for weight loss – is getting into the medication business.

The company is purchasing a yearold telehealth startup called Sequence, which will give patrons the option to request anti-obesity medication along with their monthly membership.

The details of precisely how the medical care will be integrated into the behavioral health system have yet to be worked out, said Gary Foster, WeightWatc­hers’ chief scientific officer.

But after the deal closes this spring, WeightWatc­hers’ members will get the option to request a telehealth visit to discuss medication. If eligible, Sequence’s technology will speed the process of applying for insurance coverage for the drugs.

“As a brand leader, we have a responsibi­lity to … look at recent advances in the science and treatment of obesity and think about if and how they fit in our WeightWatc­hers’ ecosystem,” Foster said. “We decided this was one that was worth incorporat­ing.”

Obesity expert Dr. Caroline Apovian said she’s skeptical weight loss can be well managed without an in-person physical exam, but praised the move into medication.

“Kudos to them for doing this,” said Apovian, who co-directs the Center for Weight Management and Wellness at Brigham and Women’s Hospital.

A new class of drugs has been shown to help people shed 15% to 20% of their excess weight.

“Lifestyle (change) is very important but it’s not going to help people keep the weight off and that’s the key,” said Apovian, who serves on the scientific advisory board of Novo Nordisk, which makes one of the new drugs.

WeightWatc­hers will acquire Sequence for a total of $132 million in a deal scheduled to be finalized this spring, according to a joint news release from the two companies.

Sequence, which launched in late 2021, had about $25 million in annual revenue from approximat­ely 24,000 members as of last month. It offers an automated preapprova­l process to help patients get coverage for weight-loss medication­s.

“For those who have insurance coverage, you’ll be able to ascertain insurance coverage in short order,” which can be challengin­g for many medical offices to handle and has been a major roadblock for accessing medication­s, Foster said.

Today, only about 20% to 30% of private insurance plans cover weight-loss medication­s and government programs do not, Apovian said.

The drug Wegovy (genericall­y called semaglutid­e), which can help people lose as much as 15% of their body weight, costs about $1,300 a month. Mounjaro (tirzepatid­e), a $1,000-amonth diabetes medication being tested for weight loss, has shown it can help people lose about 20%.

Foster said he also was impressed with how Sequence’s customers spoke about the quality of the service and how easy it was for them to access care. The company has a limited history and did essentiall­y no marketing, he said, but still managed to accumulate more than 20,000 members.

“We’re always looking for how we can better serve people with weight management that is scalable, science-based and effective,” Foster said.

Weight-loss medication­s aren’t for everyone, he said, but for the people for whom they’re appropriat­e “we want to make sure that process gets done well.”

In one study of 150 WeightWatc­hers members, participan­ts lost about 6% of their body weight after six months, with one-third of the most active members losing at least 10%.

The new generation of medication­s, which manipulate natural hormones that regulate fullness, can lead to much greater weight loss.

Foster described this class of drugs, called GLP-1 agonists, as “a significant inflection point in the treatment of obesity.”

While most people who lose weight through diet and exercise regain the weight, medication­s are expected to be taken indefinitely to keep pounds from creeping back.

“This is not a short-term fix,” said Dr. Christophe­r Still, an obesity medicine expert and director of the Geisinger Obesity Institute. “Once you stop these medication­s, you take away that barrier of appetite and your appetite comes back and the weight comes back.”

WeightWatc­hers’ purchase is “a great idea,” according to Dr. Yoni Freedhoff, a Canadian weight-loss specialist, who takes some funding from Novo Nordisk.

“We have a world that treats obesity like a disease of willpower and a health care system that’s not trained in the medical management of obesity,” he said.

In the past, WeightWatc­hers has contribute­d to the false notion that lifestyle change can lead to enduring weight loss for many people, Freedhoff said, while in reality thousands of genes and hormones undermine weight loss efforts. “Thankfully, we are finally in an era of safe, useful, tolerable medication­s that can lead to long-term clinically meaningful change.”

 ?? RICHARD DREW/AP ?? WeightWatc­hers will acquire telehealth startup Sequence for a total of $132 million in a deal scheduled to be finalized this spring. Members will get the option to request a telehealth visit to discuss medication.
RICHARD DREW/AP WeightWatc­hers will acquire telehealth startup Sequence for a total of $132 million in a deal scheduled to be finalized this spring. Members will get the option to request a telehealth visit to discuss medication.

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