Birth defects seen in 6% of U.S. Zika pregnancies

Study’s findings echo reports in other countries.

NEW YORK — A U.S. study of Zika-infected pregnancies found that 6 percent of them ended in birth defects. The rate was nearly twice as high for women infected early in pregnancy.

I t ’s t he f i r s t publi shed research on outcomes in the United States, and the authors say the findings echo what’s been reported in Brazil and other countries with Zika outbreaks.

It also showed that the rate of birth defects was the same for women who didn’t show any signs of infection during their pregnancy as those that did.

That’s important because most people who get infected don’t have any symptoms, said Margaret Honein of the Centers for Disease Control and Prevention, one of the study’s authors. Symptoms include fever, rash, joint pain and red eyes.

“Pregnant women and their health care providers need to understand there is a risk” for infected women who never seemed to get sick, she said Wednesday.

The study came from a U.S. registry that the CDC started earlier this year to monitor pregnant women with Zika. All of the women included were infected while in a Zika outbreak country or had sex with someone who got Zika overseas. Zika is primarily spread through mosquito bites.

Out of the 442 pregnancies, 26 had birth defects linked to Zika, or 6 percent. Among women who were infected in the first three months, the figure rose to 11 percent.

Twenty-one babies were born with birth defects; five of the cases were stillbirths, miscarriages or abortions — the researchers did not say how many of each.

Defects included microcephaly, in which a baby’s skull is small because the brain hasn’t developed properly.

Included in the registry are any foreigners who were in the U.S. when their pregnancy ended. The study did not include the U.S. territory of Puerto Rico, which has been hit hard by Zika.