The Riverside Press-Enterprise

Weightwatc­hers to add prescripti­on medicine

Sequence acquisitio­n taps into market that addresses obesity

- By Michelle Chapman Associated Press writer Jonel Aleccia contribute­d to this report.

Weightwatc­hers’ stock soared Tuesday after the company said it is getting into the prescripti­on drug weight loss business with the acquisitio­n of Sequence.

Sequence is a telehealth provider that offers users access to drugs used to treat diabetes and obesity under the brand names including Ozempic, Wegovy and Trulicity. The drugs all work by the same mechanism: They trigger the release of insulin, block sugar production in the liver and suppress appetite.

Weightwatc­hers offers subscriber­s meal plans with the goal of losing excess weight. With the acquisitio­n of Sequence, it is tapping into a red-hot market for prescripti­on drugs that address obesity, and broadening what it offers to customers.

Shares of WW Internatio­nal Inc. surged almost 70% Tuesday.

“It is our responsibi­lity, as the trusted leader in weight management, to support those interested in exploring if medication­s are right for them,” CEO Sima Sistani said in a statement late Monday.

Ozempic and Wegovy are different versions of the same drug, known as semaglutid­e. They’re both given as once-weekly injections. Ozempic is approved only to treat diabetes, although it has been increasing­ly prescribed for off-label use. Wegovy was approved in 2021 to treat obesity in adults, and late last year to treat the condition in adolescent­s 12 and older.

In a clinical trial, adults who used Wegovy lost about 15% of their initial body weight, while teens lost slightly more. For best results, the drugs should be combined with diet and exercise, experts say. Trulicity is a different drug, dulaglutid­e, used to treat diabetes in adults and children ages 10 and older. It’s not approved to treat obesity.

The off-label use of semaglutid­e, spurred by social media posts, led to a shortage of the drug for most of last year. Novo Nordisk said supplies are being replenishe­d, but many diabetes patients still report trouble accessing the drugs they need.

Both Ozempic and Wegovy can cause possible side effects, the company reported. They include possible thyroid cancer, pancreatit­is, kidney and gallbladde­r problems. The most common side effects are nausea, vomiting, diarrhea, stomach pain and constipati­on.

Obesity prevalence rose from 30.5% from 1999-2000 to 41.9% for 2017 through March 2020, according to the Centers for Disease Control and Prevention. The prevalence of severe obesity surged from 4.7% to 9.2% for the same periods.

The estimated annual medical cost of obesity in the U.S. was almost $173 billion in 2019 dollars, according to the CDC. Annual medical costs for adults who had obesity were $1,861 higher than medical costs for people with healthy weight.

“This deal brings access to prescripti­on drug solutions for weight loss to WW’S historical focus on behavior modificati­on model,” UBS analyst Michael Lasser wrote. “This is a significan­t change in the business. While the deal could bring considerab­le upside, it also carries sizable risks.”

Lasser said that WW’S business has been disrupted over the last several years and is now trying to take big steps to course correct.

“We think it will take time to see if this action really produces a change in the company’s fortunes,” he said.

WW Internatio­nal, based in New York, will pay $106 million for Sequence, which served about 24,000 members across the U.S. as of February, with annual revenue of about $25 million.

The acquisitio­n is expected to close in the fiscal second quarter.

 ?? RICHARD DREW THE ASSOCIATED PRESS ?? Weightwatc­hers shares soared nearly 70% Tuesday after the company said it was acquiring drug weight loss company Sequence for $106 million. A Weightwatc­hers, its logo shown on a mobile phone Tuesday, offers subscriber­s meal plans with the goal of losing weight.
RICHARD DREW THE ASSOCIATED PRESS Weightwatc­hers shares soared nearly 70% Tuesday after the company said it was acquiring drug weight loss company Sequence for $106 million. A Weightwatc­hers, its logo shown on a mobile phone Tuesday, offers subscriber­s meal plans with the goal of losing weight.

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