The Saratogian (Saratoga, NY)

A Pipeline of Potential Profits

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When evaluating drug makers as possible investment­s, it’s important to check out their pipelines of products in developmen­t. It can take a decade or longer for a drug to pass all clinical trials and get approved by the Food and Drug Administra­tion (FDA), and many drugs in developmen­t never end up approved for sale. Thus, a big pipeline is promising, because it’s likely that at least some drugs will make it to market.

For a hefty pipeline, check out the Swiss pharmaceut­ical giant Roche (NasdaqOTH: RHHBY). It sports about 150 clinical programs in developmen­t, including some for combinatio­n treatments based on the company’s already-approved drugs. Cancer drug Tecentriq, for example, is included in more than a dozen studies in combinatio­n with other drugs.

Roche also leads its industry with 14 of its drugs in developmen­t designated by the FDA as “breakthrou­gh therapies” — with their early stage clinical data suggesting a vast improvemen­t over existing options.

Looking beyond 2018, Roche has a potential wave of regulatory filings on the way and could submit 25 drugs for approval. Among the most notable candidates are autoimmune disease drug etrolizuma­b and two experiment­al Alzheimer’s disease drugs.

Meanwhile, Roche recently won regulatory approval for multiple sclerosis drug Ocrevus. The drug is expected to generate sales of more than $3 billion.

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