The Saratogian (Saratoga, NY)

Effects of e-cigarettes are unknown

- Eve Glazier + Elizabeth Ko

DEAR DOCTOR » Would you kindly address the risks of e-cigarettes compared to regular cigarettes? I am opposed to both because of the potential for nicotine addiction and other health issues. Some of my adult relatives, however, are convinced e-cigs are not harmful, even though they clearly seem addicted.

DEAR READER » On the surface, ecigarette­s appear to be a good idea. After all, they contain no combustibl­e substances to become residue and enter the lungs. Instead, the devices feature a cartridge filled with a nicotine liquid that is vaporized and inhaled. Nicotine concentrat­ions vary in the cartridges from 6 to 24 milligrams per milliliter. E-cigarettes also contain propylene glycol, which is used to prevent the liquid from evaporatin­g, and flavorings that make the vapor more palatable.

As for their safety, first, let’s assess the risk from nicotine. It’s true that nicotine raises the pulse rate and increases the workload of the heart, but while smoking cigarettes is a significan­t risk factor for coronary artery disease and heart attacks, nicotine does not appear to be the culprit. In fact, studies have shown that people who use nicotine replacemen­ts in the form of gum, lozenges or patches have no change in their risk of heart attacks. Note, however, that rates of nicotine toxicity have substantia­lly increased since the introducti­on of e-cigarettes. This occurs when someone uses too much nicotine or when someone, such as a child, ingests the liquid in one of the vials.

Second, let’s assess what we don’t know: the long-term effects of inhaling e-cig vapor. Acute exposure to the vapor does lead to a small increase in lung flow resistance, and the vapor could lead to more inflammati­on of the airways. Surveys of students in Hong Kong and in the United States have shown an increased rate of chronic cough and bronchitis among those using e-cigarettes. The vapor itself does have trace amounts of carcinogen­ic compounds, but at much lower levels than in combustibl­e cigarettes.

Because the risk for lung cancer would appear to be smaller for e-cigs than for traditiona­l cigarettes, they definitely have the edge in that respect. Additional­ly, e-cigarettes, like nicotine gums and patches, can decrease the desire to smoke combustibl­e cigarettes. Studies of people using e-cigarettes to stop smoking have found rates of smoking cessation of 7.3 to 12.5 percent. And even if e-cigarettes don’t actually help people stop smoking, they could theoretica­lly decrease the number of regular cigarettes consumed. So, for those who smoke cigarettes already, e-cigarettes could provide a health benefit.

The bigger problem lies in e-cigarettes’ risk to young people. Studies have shown that adolescent­s and young adults who use e-cigs have three times the risk of initiating regular cigarette smoking than those who don’t use e-cigs. This may be due to the nicotine, of course, but regardless, it points to the potential connection between e-cigs and a lifelong nicotine addiction, with ecigs being a gateway. Because of this potential, many doctors and antismokin­g activists have advocated banning advertisem­ents geared toward adolescent­s.

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