The Sentinel-Record

Type 2 diabetes can be reversed, but reality is not that simple

- Copyright 2017, Universal UClick for UFS (Robert Ashley, M.D., is an internist and assistant professor of medicine at the University of California, Los Angeles.) (Send your questions to askthedoct­ors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media

Dear Doctor: Can Type 2 diabetes be reversed? My son was recently diagnosed with it, but I'm not sure he's taking it seriously enough.

Dear Reader: I understand your concern: Clearly, your son -- and everyone with diabetes -- should do whatever they can to combat the disease. Chronicall­y elevated blood sugar leads to atheroscle­rosis, increasing the risk of heart attacks, strokes and vascular disease in the legs. It also damages the nerves and kidneys, leading to a loss of sensation and kidney failure. Controllin­g the disease, though difficult, is not impossible and should be paramount.

Even reversing the disease is doable. As proof, consider the effects of bariatric (weight loss) sur- gery among people with Type 2 diabetes. They quickly go into remission.

If surgery seems too dramatic, consider the non-surgical evidence from a 2015 study in which

29 patients consumed a liquid diet of 624 to 700 calories per day for eight weeks. In the United

States, the reported average caloric intake for a man is 2,600 and in women it is about 1,800; for people with Type 2 diabetes, it's often much higher. After eight weeks of calorie restrictio­n, the average study participan­t lost about 32 pounds.

Among those who had had diabetes for less than four years, 87 percent reversed their fasting blood sugars to non-diabetic levels. Among those who had had diabetes for more than eight years, 50 percent were able to reverse blood sugars to non-diabetic levels. Blood pressure and cholestero­l numbers also improved and the participan­ts were able to tolerate the calorie restrictio­n well.

A 2016 study looked at what happened to these patients after they returned to a normal-calorie diet. All participan­ts received dietary counseling and, six months after the initial start of the study, they had regained -- on average -- only 2 pounds of the 32 pounds they lost during fasting. Those who had reversed their diabetes were able to maintain their blood sugar at the same level even after returning to a normal-calorie diet. Even those who were not able to reverse their diabetes had lower blood sugar levels than before the study.

A current study that won't have complete data until 2018 has followed 140 patients who adhered to 12 weeks of an 825-to-853-calorie diet; it will follow them as they then try to maintain a balanced diet for the next 92 weeks. The results are expected to give Type 2 diabetics hope of reversing diabetes with initial calorie restrictio­n, followed by a balanced diet.

These are tightly controlled university studies and may be difficult to replicate outside of a well-conducted clinical trial. However, newly diagnosed Type 2 diabetic patients eventually may be given directions for a low-calorie diet, followed by a diet overseen by a nutritioni­st.

In the meantime, to reverse his diabetes, your son needs to start by eliminatin­g foods with added sugar. This seems obvious, but it takes self-control. Cookies, candies, cakes, doughnuts, ice cream, sodas and juices should have no place in his diet. He should also stay clear of low-fiber carbohydra­tes, especially snack foods. If he's diligent with his diet, he can reverse a disease that has become an epidemic within our country.

So the answer is: Yes, Type 2 diabetes can be reversed, as can the obesity that leads to it. But reality itself isn't that simple.

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