The Standard Journal

Flu may be spread just by breathing

A new medical study outlines how the concentrat­ion of flu virus in exhaled breath vastly increases the risk of infection.

- By Tracy Seipel

A new study released in the Proceeding­s of the National Academy of Sciences reveals that we may pass the flu to others just by breathing.

The study — which included researcher­s from San Jose State University and UC Berkeley — provides new evidence for the potential importance of the flu’s airborne transmissi­on because of the large quantities of infectious virus researcher­s found in the exhaled breath from people suffering from flu.

“The study findings suggest that keeping surfaces clean, washing our hands all the time, and avoiding people who are coughing does not provide complete protection from getting the flu,” Sheryl Ehrman, dean of the College of Engineerin­g at San Jose State University, said in a statement.

“Staying home and out of public spaces could make a difference in the spread of the influenza virus.”

The study was done at the University of Maryland during the flu season of December 2012 through March 2013. Researcher­s there recruited 178 volunteers, mostly students, who were within the first three days of the flu’s onset.

Over four months, researcher­s captured and characteri­zed the flu virus in exhaled breath from 142 of the volunteers who had confirmed cases of the flu, as the volunteers breathed naturally, talked, coughed or sneezed.

The researcher­s then assessed the infectivit­y of naturally occurring flu aerosols, tiny droplets that stay suspended in the air for a long time.

The study said par- ticipants provided 218 swabs from the upper part of their throats that lies just behind the nose, and the same number of 30-minute samples of exhaled breath, spontaneou­s coughing, and sneezing on the first, second, and third days after the onset of flu symptoms.

The analysis of the infectious virus recovered from these samples showed that a significan­t number of flu patients routinely shed infectious virus, not merely detectable ribonuclei­c acid, or RNA, into aerosol particles small enough to present a risk for airborne transmissi­on.

Surprising­ly, the study said, 11 of the 23 fine aerosol samples acquired in the absence of coughing had detectable viral RNA, and 8 of these 11 contained infectious virus, suggesting that coughing was not necessary for infectious aerosol generation in the fine aerosol droplets.

“We found that flu cases contaminat­ed the air around them with infectious virus just by breathing, without coughing or sneezing,” Dr. Donald Milton, professor of environmen­tal health in the University of Maryland School of Public Health, said in a statement.

The researcher­s believe that their findings could be used to improve mathematic­al models of the risk of airborne flu transmissi­on from people with flu symptoms. The results could help develop more effective public health interventi­ons and to control and reduce the impact of influenza epidemics and pandemics.

‘We found that flu cases contaminat­ed the air around them with infectious virus just by breathing, without coughing or sneezing.’

Dr. Donald Milton

University of Maryland

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