GIANTS GAMEDAY

Who: Giants (1-7) at 49ers (0-9), Sunday 4:25 p.m. ET (FOX)

Line: New York by 2.5.

History: The Giants are 20-19 all-time against the Niners. They’ve won three of the last four meetings, including the 2012 NFC Championship Game. This marks New York’s first trip to San Francisco’s new field, Levi’s Stadium, which opened in 2014.

Key Matchups: Giants C Brett Jones versus 49ers DT DeForest Buckner . ... Giants WR Sterling Shepard versus 49ers CB Leon Hall . ... Giants DE Jason PierrePaul versus 49ers LT Trent Brown. ... Giants LBs versus 49ers RB Carlos Hyde.

INJURY REPORT

Giants: OUT: LB B.J. Goodson (ankle), LB Devon Kennard (quad), LB Keenan Robinson (quad). DOUBTFUL: CB Donte Deayon (knee). QUESTIONABLE: LB Jonathan Casillas (neck), LB Calvin Munson (quad), DE Olivier Vernon (ankle), DE Kerry Wynn (ankle).

49ers: OUT: TE George Kittle (ankle), LB Elijah Lee (knee), DE Aaron Lynch (calf), WR Trent Taylor (ribs). QUESTIONABLE: DE Solomon Thomas (knee), CB K’Waun William (quadricep). GIANT FACTS: Eli Manning will make his 208th consecutive start Sunday, which will tie Peyton for the second-longest streak by a quarterback in NFL history . ... Jonathan Casillas, a New Brunswick High School product, is set to play in his 100th career game since being undrafted out of Wisconsin in 2009 . ... The Giants’ defense, which allowed the Rams to convert 6-of-12 third downs last Sunday, ranks 23rd in the league in opponent third-down success rate (41.7 percent).

The Prediction: The off-field turmoil keeps rising and the Giants’ remain besieged by injuries. A loss this week would truly be rock bottom for the New York’s sinking ship. With that said, San Francisco is the only team in the NFL more abysmal. The 49ers have virtually no playmakers with Pierre Garcon done for the year, and the Giants should be able to generate tons of pressure against an offensive line that let up five sacks to the Cardinals last week. There are simply no excuses for Big Blue on Sunday. GIANTS 20, NINERS 13.