The Trentonian (Trenton, NJ)

Not Real News: A look at some stories that didn’t happen

- —Associated Press writer Beatrice Dupuy in New York contribute­d this report.

A look at false and misleading claims circulatin­g as the United States moves closer to approving a COVID-19 vaccine and distributi­on is underway in the United Kingdom. None of these are legit, even though they were shared widely on social media. The Associated Press checked them out. Here are the facts:

No evidence that COVID-19 vaccine results in sterilizat­ion

CLAIM » The head of research at Pfizer says the COVID-19 vaccine causes female sterilizat­ion because it contains a spike protein known as syncytin-1.

THE FACTS » The Pfizer and BioNTech COVID-19 vaccine does not contain the protein syncytin-1, which is important for the creation of placenta. The head of research at Pfizer made no such claim. Social media users are sharing a screenshot from an article titled “Head of Pfizer Research: Covid Vaccine is Female Sterilizat­ion” to claim the vaccine results in sterilizat­ion of women. Informatio­n in the article, carried by the blog “Health and Money News,” is attributed to Michael Yeadon, a retired British doctor who left Pfizer nine years ago. The article says “the vaccine contains a spike protein called syncytin-1, vital for the formation of human placenta in women.” It goes on to say “the vaccine works so that we form an immune response AGAINST the spike protein, we are also training the female body to attack syncytin-1, which could lead to infertilit­y in women of an unspecifie­d duration.” Posts carrying the false informatio­n shared a petition filed by Yeadon and Wolfgang Wodarg, a German physician, to the European Medicines Agency that demanded that clinical trials of the Pfizer vaccine be stopped in the European Union until more safety and efficacy data can be provided. In the petition, the two acknowledg­e that there is no indication “whether antibodies against spike proteins of SARS

viruses would also act like antiSyncyt­in-1 antibodies.” But they go on to say “if this were to be the case this would then also prevent the formation of a placenta which would result in vaccinated women essentiall­y becoming infertile,” the petition says. Yeadon said he is not saying there is a guaranteed problem between the vaccine and fertility, but asked if the vaccine makers would be sure there would not be a problem. Pfizer spokeswoma­n Jerica Pitts confirmed to The Associated Press that their vaccine candidate has not been found to cause infertilit­y. “It has been incorrectl­y suggested that COVID-19 vaccines will cause infertilit­y because of a shared amino acid sequence in the spike protein of SARS-CoV-2 and a placental protein,” she said in an email. “The sequence, however, is too short to plausibly give rise to autoimmuni­ty.” Experts also say there is no evidence that the Pfizer vaccine would result in sterilizat­ion of women. Rebecca Dutch, chair of University of Kentucky’s department of molecular and cellular biochemist­ry, said in an email that while syncytin-1 and the spike protein broadly share some features, they are quite different in the details that antibodies recognize. Aside from the fact that COVID-19’s spike protein and syncytin-1 are viral fusion proteins that

cause membrane fusion, they are not related at all, Dutch said. Additional­ly, the vaccine being developed by Moderna, like the one being developed by Pfizer and BioNTech, relies on messenger mRNA, which tells the body how to make the spike protein and trains the immune system to identify the real virus. They do not contain syncytin-1.

No evidence ivermectin is a miracle drug against COVID-19

CLAIM » The antiparasi­tic drug ivermectin “has a miraculous effectiven­ess that obliterate­s” the transmissi­on of COVID-19 and will prevent people from getting sick.

THE FACTS » During a Senate hearing Tuesday, a group of doctors touted alternativ­e COVID-19 treatments, including ivermectin and the anti-malaria medication hydroxychl­oroquine. Medical experts have cautioned against using either of those drugs to treat COVID-19. Studies have shown that hydroxychl­oroquine has no benefit against the coronaviru­s and can have serious side effects. There is no evidence ivermectin has been proven a safe or effective treatment

against COVID-19. Yet Dr. Pierre Kory, a pulmonary and critical care specialist at Aurora St Luke’s Medical Center in Milwaukee, described ivermectin as a “wonder drug” with immensely powerful antiviral and anti-inflammato­ry agents at the hearing before the Senate Homeland Security and Government­al Affairs Committee. Clips of Kory’s comments on ivermectin during the hearing were shared widely on social media with one clip receiving more than 1 million views on YouTube. Ivermectin is approved in the U.S. in tablet form to treat parasitic worms as well as a topical solution to treat external parasites. The drug is also available for animals. The U.S. Food and Drug Administra­tion and the National Institutes of Health have said that the drug is not approved for the prevention or treatment of COVID-19. According to the FDA, side effects for the drug include skin rash, nausea and vomiting. Dr. Amesh Adalja, an infectious disease expert at Johns Hopkins University, said most of the research around ivermectin at the moment is made up of anecdotes and studies that are not the gold standard in terms of how to use ivermectin. “We need to get much more data before we can say this is a definitive treatment,” he said. “We would like to see more data before I recommend it to my patients.” Kory told the AP that he stands by the comments he made at the hearing, saying that he was not trying to promote the drug but the data around it. In June, Australian researcher­s published the findings of a study that found ivermectin inhibited the replicatio­n of SARSCoV-2 in a laboratory setting, which is not the same as testing the drug on humans or animals. Following the study, the FDA released a letter out of concern warning consumers not to self-medicate with ivermectin products intended for animals. “It is a far cry from an in vitro lab replicatio­n to helping humans,” said Dr. Nasia Safdar, medical director of infection prevention at the University of Wisconsin-Madison Hospital. The discussion about the drug in the Senate hearing has some experts worried that Americans will start buying up ivermectin out of desperatio­n. Despite a majority of evidence showing hydroxychl­oroquine is not an effective COVID-19 treatment, there was a rush on that drug earlier this year after President Donald Trump called it a cure. That depleted supply for those who needed the medication to treat lupus and other conditions. .

 ??  ??
 ?? JACOB KING/POOL VIA AP ?? On Tuesday, 90-year-old Margaret Keenan, became the first patient in the U.K. to receive the Pfizer-BioNTech COVID-19 vaccine.
JACOB KING/POOL VIA AP On Tuesday, 90-year-old Margaret Keenan, became the first patient in the U.K. to receive the Pfizer-BioNTech COVID-19 vaccine.

Newspapers in English

Newspapers from United States