The Union Democrat

Some people are taking an anti-parasitic to treat COVID. Here’s why that’s bad

- By KATIE CAMERO The Charlotte Observer

Some people itching to get their hands on a COVID-19 cure are putting themselves in danger for taking unprescrib­ed doses of ivermectin, an anti-parasitic drug used to treat diseases such as river blindness or scabies in people and prevent heartworm disease and other infestatio­ns in animals.

The drug has been flying off the shelves of farm supply stores and veterinary offices as people, mostly those who refuse to get vaccinated, search for unconventi­onal ways out of the pandemic.

Yet, several federal and internatio­nal health agencies, including the U.S. Food and Drug Administra­tion, the National Institutes of Health and the World Health Organizati­on, have advised against using ivermectin to treat or prevent COVID-19 outside of controlled clinical trials.

That’s because taking large unprescrib­ed doses intended for animals can seriously harm your health.

“Let’s say it was manufactur­ed for a large horse, but a human takes it, it can create low blood pressure, rapid heart rates, seizures; there are even episodes where you can see layers of your skin fall off. It can damage the liver, and there’s vision loss that can be associated,” Dr. Shane Speights, site dean at the New York Institute of Technology College of Osteopathi­c Medicine, told KAIT8.

“Data is just not good on ivermectin right now for the treatment of COVID. One of the drug manufactur­ers even said don’t use it,” Speights told the outlet. “Right now, the only answer to COVID is to be fully vaccinated.”

What do studies reveal about ivermectin and COVID-19?

Misconcept­ions about the drug’s coronaviru­s healing abilities began to spread when a handful of studies found positive trends in patients after taking the drug, particular­ly one non-peer reviewed paper that said ivermectin can lower COVID-19 death rates by more than 90%.

That study has since been withdrawn from the research website following reports of plagiarism and data manipulati­on that “are now under formal investigat­ion.”

Separate research published in June last year found that ivermectin reduced the amount of coronaviru­s in a laboratory dish by 5,000-fold after two days. Some studies showed the drug helped COVID-19 patients recover faster and reduced inflammati­on, while others showed no benefits or worsening of disease.

But “most of these studies had incomplete informatio­n and significan­t methodolog­ical limitation­s, which make it difficult to exclude common causes of bias,” according to the NIH, including small sample sizes, inconsiste­ncies in the reporting of disease severity and conflictin­g data as patients received multiple medication­s at once.

“The way that [ivermectin] works is it actually paralyses the worm by attacking the nerve and muscle cells,” Speights told KAIT8. “COVID is [caused by] a virus. COVID doesn’t have nerve or muscle cells, so the mechanism in which the drug works wouldn’t work for a virus.”

A WHO group of experts analyzed 16 randomized controlled trials including a total of 2,407 inpatients and outpatient­s with COVID-19 and concluded that evidence of the drug’s ability to improve disease outcomes is of “very low certainty.” The group didn’t look into whether ivermectin can prevent COVID-19.

“We have a hospital with dozens and dozens of patients that have taken ivermectin that is in with COVID pneumonia. I see this every day,” Dr. Robin Trotman, an infectious disease specialist in Missouri, told Fox2now. “We have things that work. The [monoclonal antibodies] clearly work, if you’re in the hospital steroids clearly work. But this one, I wish it worked, but the evidence is pretty clear.”

Incorrectl­y prescribed ivermectin can cause serious side effects.

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