USA TODAY US Edition

Virus is on cusp, US warns

Nation would see ‘severe’ disruption to daily life

- John Bacon and Ken Alltucker

A federal health official warned Tuesday that the deadly coronaviru­s could cause “severe” disruption­s in the USA as global experts struggled to fend off the outbreak and avoid a pandemic.

“Disruption to everyday life may be severe,” Nancy Messonnier, director of the Centers for Disease Control and Prevention’s National Center for Immunizati­on and Respirator­y Diseases, warned at a news conference Tuesday.

Schools could be closed, mass public gatherings suspended and businesses forced to have employees work remotely, she said.

Messonnier said the coronaviru­s has caused sickness and death and sustained person-to-person transmissi­on – two of the three factors for a pandemic.

“As community spread is detected in more and more countries, the world moves closer to meeting the third criteria – worldwide spread of the new virus,” Messonnier said.

Although the World

Health Organizati­on determined Monday that the term pandemic “did not fit the facts,” experts said it very soon could.

Dennis Carroll, former director of the U.S.

Agency for Internatio­nal Developmen­t’s

Global Health Security and Developmen­t Unit, credited China’s “extraordin­ary control measures” with delaying the spread of the virus, but he said avoiding a pandemic is “very unlikely.”

“The dramatic uptick of cases in South Korea, Iran and Italy are reflective of a self-sustaining spreading of the virus and a clear message that the horse is out of the barn,” Carroll, who leads the Global Virome Project science cooperativ­e, told USA TODAY.

Melissa Nolan, a medical doctor and professor of

epidemiolo­gy at the University of South Carolina’s Arnold School of Public Health, cited new clusters in Iran, which faces at least 95 cases and has had 16 deaths, and Italy, which is dealing with 322 cases.

“If we continue to see focalized local transmissi­on in areas outside of China, the WHO will need to reconvene,” Nolan told USA TODAY on Tuesday. “We are very close to seeing this virus becoming a pandemic.”

Nolan said responses to the outbreaks in Iran and Italy could help health officials in other countries prepare their own medical and quarantine policies before an outbreak. That is crucial, said Robert Glatter, an emergency physician at New York’s Lenox Hill Hospital who fears the world is on the “cusp” of a pandemic.

“Trying to contain a disease which spreads like influenza, in this case COVID-19, is almost impossible,” he said. “We are talking about rapid-fire and sustained transmissi­on.”

That means redirectin­g the focus from containmen­t measures to preparing for treatment of big numbers of sick patients with antivirals while continuing the effort to develop an effective vaccine, he said.

Beyond an epidemic, which involves a defined region, a pandemic has global impact. It can be a moving target – there is no threshold, such as number of deaths or infections.

WHO, which could make a pandemic declaratio­n, describes a pandemic as “an epidemic occurring worldwide, or over a very wide area, crossing internatio­nal boundaries and usually affecting a large number of people.”

WHO Director-General Tedros Adhanom Ghebreyesu­s does not want to go there.

“I have spoken consistent­ly about the need for facts, not fear,” Tedros said. “Using the word ‘pandemic’ now does not fit the facts, but it may certainly cause fear.”

Ogbonnaya Omenka, an assistant professor and public health specialist at Butler University’s College of Pharmacy and Health Sciences, said he understand­s the concerns. The main implicatio­n of declaring a pandemic is requiring, or at least further urging, national government­s to prepare facilities and health workers to treat a lot of patients, he told USA TODAY.

“Not only is this costly, it may also trigger panic,” he warned. “Countries may as well put in place these plans without the official announceme­nt.”

Tedros stressed that a pandemic declaratio­n would not eliminate the need for health authoritie­s to continue testing, limiting contact with the sick and encouragin­g frequent hand washing – the front-line defense.

He noted that cases in China have declined for the past three weeks. In Wuhan, where health services were stretched when the outbreak began in December, the fatality rate is 2%-4%. Elsewhere in China, it’s less than 1%.

This season’s flu death rate in the USA is less than 0.1%, according to the CDC. More than 30 million Americans have suffered from the flu this season, while the global number of confirmed coronaviru­s cases hasn’t reached 100,000.

There is a vaccine for the flu. Labs around the world are scrambling to develop one for the coronaviru­s. President Donald Trump requested $2.5 billion to fight the virus, including more than $1 billion toward developing a vaccine.

At a news conference Tuesday in India, Trump tried to tamp down concerns, saying the virus was “very well under control in our country.” Confirmed cases totaled 57 Tuesday, and no one has died in the USA, although one American died in Wuhan.

“We have very few people with it, and ... the people are all getting better,” Trump said.

Messonnier acknowledg­ed the CDC struck a more urgent tone in warnings about the virus in the USA. The proliferat­ion of coronaviru­s in countries outside China raised the agency’s expectatio­ns the virus will spread here.

“People are concerned about this situation – I would say rightfully so,” she said. “But we are putting our concerns to work preparing. Now is the time for businesses, hospitals, communitie­s, schools and everyday people to begin preparing as well.”

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