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❚ “Real tragedies”: Q&A with former CDC Director Tom Frieden.

Former CDC chief: ‘I feel less safe’ because agency isn’t centrally involved

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Dr. Tom Frieden, one of the nation’s leading experts on public health and infectious disease, spoke with USA TODAY’s Editorial Board on Tuesday as New York Gov. Andrew Cuomo warned that the new coronaviru­s is “spiking” in his state and President Donald Trump said he wants “the country opened up and just raring to go by Easter.” Frieden, 59, is a former director of the Centers for Disease Control and Prevention and former New York City health commission­er. Questions and answers have been edited for length and clarity:

Q. Where are we on the arc of this outbreak, and where are we headed?

A. Sadly, New York City is in the rapid accelerati­on phase, and I fear this week will bring two things. The first is extreme stress on our intensive care capacity, with the possibilit­y that there will be not enough intensive care beds for the patients who need them. And the second is an increasing number of infected health care workers. I already know medical school classmates and colleagues, and quite a few health care workers, who are infected in New York City. These are the two real tragedies that we’re seeing now, and it’s a warning to the country that you need to really take this seriously and take appropriat­e action so that you can mitigate the impact as effectivel­y as possible.

Q. Should the whole country be on lockdown, or should states and localities make their own decisions?

A. Actually, it’s very important that different decisions are made in different places. This is one of the areas where I think we really have to get it right. We need to think about this with three essential phases. First, the containmen­t phase, where you’re really trying to prevent a Wuhan-, Italy- or New York City-type situation. Second, the mitigation phase, which is what we’re in now in New York City, where you really need to turn off the tap of more infections while you aggressive­ly strengthen your health care and public health systems. And third, the suppressio­n phase, where if you can drive down the cases, you’re then going to be dealing with little clusters of cases and keep trying to aggressive­ly respond to those.

Q. How long will we need to hunker down?

A. This is something that will be determined based on a couple of things. It’s very important to understand the reasons for the sheltering in place. One, everyone has seen the “flattening the curve” idea, so we don’t overwhelm the health care system. The second, which is equally important, is to ramp up our health care and public health systems so the risk that it will get out of hand again comes down. So I think it’s going to be different in different places. Instead of opening the floodgates, we’ll be turning the faucet. And it’ll be different for different people. People at higher risk are going to have to hunker down for longer, and it’ll be different for different parts of the economy and different types of work.

Q. What about reopening schools?

A. Schools need to be looked at very carefully, because we don’t know if kids commonly spread this infection, and therefore, we don’t know if it’s really very helpful to close schools. You also need to recognize that in schools there will both staff and students who are medically vulnerable, and they will need to be able to participat­e by distance, if at all possible. That’s just one of the many ways in which our world is changed forever with this.

Q. Can you understand why the public is confused about the severity of the threat?

A. (Even in the world’s hot spots) we estimate that maybe 3% or 4% of people are infected. So, 97% of people don’t get it, and of those who get it, 99% of people survive. So I can understand the question, “Why are we shutting the whole world for this?” This is a good question.

Q. And what’s the answer?

A. I think the answer to that has to be because of the scenes you’ve seen in Wuhan, China, the scenes you’ve seen in northern Italy and, I fear, the scenes you may soon see in New York City of overwhelme­d hospitals, of health care worker infections.

Q. You’re speaking to us from New York City. How bad is it there?

A. Remember, the severely ill patients today were infected about 10 or 12 days ago. It takes five days to get sick and about five to eight days (more) to get very sick. Unlike SARS (severe acute respirator­y syndrome) or flu, where you get sick a lot at once, this kind of crescendos. What we’re seeing in the ERs all around me in New York City today are the people who were infected two weeks ago. That means we’ve got two more weeks of cases coming in where there was still an exponentia­l increase in the number of patients, and we’re seeing doubling every day or two in New York City. So very, very concerning.

Q. Does it concern you that the CDC seems to be largely on the sidelines of this crisis?

A. This is the first outbreak in the last 75 years that CDC hasn’t been centrally involved in making decisions at the table. Not that it’s the only group that makes decisions, but it’s got unique expertise in communicat­ing those decisions. And frankly, I feel less safe because of that.

Q. Why it is so important to have CDC at the table?

A. CDC has the National Center for Immunizati­on and Respirator­y Diseases. There are 700 profession­als working there. They’ve worked, on average, for 20 years on respirator­y viral infections. They’re really good. Look, I’m an infectious disease specialist who’s worked on lung infections, and I wouldn’t trust myself to make these decisions. I would trust them to bring the best decisions out. … The public health experts are the folks at CDC, and not having them there is just not safe.

Q. How about communicat­ing with the public?

A. If you’re asking people to stay home, you have to communicat­e transparen­tly. You have to be credible. You have to give the reasoning. You have to be transparen­t. So priorities matter. And when I hear a press conference that spends close to half its time discussing border control with Mexico and Canada, which have lower case rates than the U.S. … this is no way to run a railroad. It’s certainly no way to confront an epidemic. Fighting an epidemic without CDC involved at the decision table and at the podium is like fighting with one hand tied behind your back.

Q. Why isn’t CDC playing a more prominent role?

A. I’m not there, so I can’t know for sure. I suspect that the testing problem resulted in a loss of trust and credibilit­y for CDC. I will feel more safe when I know that CDC is integrally involved in making the decisions here. … The CDC website is still the best place for informatio­n on this virus.

Q. What went wrong with the testing for COVID-19?

A. CDC made a mistake with testing. We can talk about what went wrong, not just the CDC, but also with FDA (the Food and Drug Administra­tion) not allowing hospital labs to develop their own tests quickly enough and with HHS (the Health and Human Services) and the private sector not getting into the game fast enough. All three of those legs didn’t work.

Q. Does that surprise you?

A. The CDC is the most surprising of the three, frankly, because in all prior outbreaks, this has worked extremely well. When I hear President Donald Trump say, “We inherited a broken and, frankly, terrible system of testing,” it’s just wrong. They inherited the system that has worked in every prior emergency. Now, it’s fair to say this is an emergency like no other. But CDC tests were never supposed to meet the entire need for the United States.

Q. Weren’t warning signs flashing from Wuhan?

A. I think things just seemed unreal to many people when it was happening in China. It somehow seemed like, you know, that’s over there, and it’s never gonna happen here. Then when it hit Italy, people realized, oh, this isn’t just a one-off situation. But by that point, it was really too late to do the scale-up that was needed.

Q. Are cruise ships a significan­t part of spreading diseases?

A. I don’t think many people — certainly I didn’t — recognize just how huge this industry has become. There were, I was told at any one time, on average, 99 ships out at sea with 365,000 Americans on them. Just as mosquitoes spread malaria and ticks spread Lyme disease, cruise ships have been spreading coronaviru­s.

Q. Are young people more vulnerable than we originally thought?

A. We have tens, if not hundreds, of thousands of infections already in the U.S. Kids don’t get very sick with this. But we’re hearing more and more stories of 30-year-olds, 40-year-olds, 50-year-olds, who were previously healthy, in intensive care. Q. Once you get COVID-19 and recover, will you be immune? A. I have a very good friend who was a medical school classmate. He’s got it. He tested positive. And he said, “I’m rooting for that immunity.” I said, “Don’t count on it.” We don’t know how immunity’s gonna be. This idea that you can send these now supermen and superwomen who are recovered into the line of fire because they won’t be killed by coronaviru­s, we don’t know that that’s the case.

Q. Could a treatment or vaccinatio­n be available soon?

A. We have a lot of hope that we’ll have treatments or vaccines. Treatments may come a lot sooner than vaccines, but still some months away. Antibody treatment is a promising one. It’s hard to scale up, so we don’t know if it’s effective. We don’t know that if you develop antibodies, you’re protected against this.

Q. And vaccines?

A. It’s usually a year to two. I would just add that we don’t know a vaccine is going to work. We shouldn’t have certainty about this. We’ve been trying for an AIDS, a TB (tuberculos­is) and a malaria vaccine for decades and we don’t have one. There was a vaccine against SARS that made it worse, not better. So, by all means, we should pull out all the stops and try to make a vaccine, but we shouldn’t count on it.

Q. This isn’t the last pandemic we’re likely to experience, is it?

A. We can’t just protect America within our borders. If China had closed the live (animal) markets after SARS in 2003, it is possible none of this would have happened. We don’t know that, but that’s possible. If Guinea in West Africa had stopped Ebola quickly, it would have taken a few weeks and a few thousand dollars; instead, it took tens of billions of dollars and killed tens of thousands of people. We know there will be another one. It’s inevitable. What’s not inevitable is that we continue to be so underprepa­red.

 ?? JASPER COLT/USA TODAY ?? “Our world is changed forever with this.”
Dr. Tom Frieden
JASPER COLT/USA TODAY “Our world is changed forever with this.” Dr. Tom Frieden

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