USA TODAY US Edition

Fauci: Positive test rates signal surge

Officials want to see less than 3% tests positive

- Ken Alltucker Contributi­ng: Mike Stucka

The nation’s top infectious disease expert said the United States faces a “difficult situation” with a rise in positive coronaviru­s tests through a wide swath of northern states as the weather cools.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said the share of positive coronaviru­s tests is increasing in the Northwest, Midwest and other northern states.

The share of tests that detect the virus is a key indicator of whether the virus is spreading or under control. Public health officials want to see less than 3% of all tests return positive. An ideal rate is less than 1%, Fauci said Tuesday during a College of American Pathologis­ts meeting.

“We’re starting to see a number of states well above that, which is often, and in fact invariably, highly predictive of a resurgence of cases,” Fauci said. A rise in the share of positive cases “we know leads to an increase in hospitaliz­ations and then ultimately an increase in deaths.”

Data from the COVID Tracking Project shows 36 states have a higher rate of tests coming back positive than the previous week. Another 41 states have higher case counts in the past week compared to a week before, an analysis of Johns Hopkins University data shows.

As the fall weather cools and people spend more time indoors, public health experts hoped “we had rather good control over infection dynamics in the country,” Fauci said. “As a matter of fact, unfortunat­ely, that’s not the case.”

Fauci said the nation is averaging between 40,000 and 50,000 new cases every day. The United States has reported more than 7.8 million cases and 215,085 deaths.

A USA TODAY analysis of Johns Hopkins data through late Monday shows 16 states set records for new cases in a week, while Kansas, North Dakota and South Dakota had a record number of deaths in a week.

Fauci said shutting down the nation again to slow the virus’ spread is something “we do not want to do.” and urged Americans to commit to public health recommenda­tions to slow SARS-CoV-2, the virus that causes COVID-19. People should wear masks, maintain a distance of at least six feet from others, avoid crowds and wash hands frequently.

The nation should know by the end of 2020 whether there is a safe and effective vaccine. With five vaccine candidates now in the late-stage clinical studies, Fauci said doses of any Food and Drug Administra­tion-authorized vaccine could be shipped by the end of the year or early 2021, first to those who are most vulnerable.

And although the developmen­t has been speedy, he said the public should be confident any vaccine will be thoroughly vetted.

An independen­t group of doctors, ethics experts and statistici­ans examine data from each vaccine candidate being studied to determine whether trials should continue. These data safety monitoring boards investigat­e adverse events reported by patients and doctors.

For example, Johnson & Johnson on Monday paused its COVID-19 vaccine trial after an unexplaine­d illness in a volunteer. Another study, run by AstraZenec­a, was halted Sept. 8 after a second participan­t was diagnosed with a neurologic­al condition.

Fauci said monitoring boards generally can decide whether a vaccine appears to harm more people than it helps or, conversely, whether the vaccine appears to be safe and more effective than a placebo.

Should a company advance to the next step and seek FDA authorizat­ion, the regulatory agency also consults with an independen­t body to review data and decide whether the vaccine is ready for widespread use.

“There are a lot of checkpoint­s in that process that I believe the general public should feel comfortabl­e a vaccine is not going to be made available unless it was agreed upon in an independen­t way to be safe and effective,” Fauci said.

 ?? AP ?? Fauci said the nation is averaging 40,000 to 50,000 new cases every day. The US has reported more than 7.8 million cases and 215,085 deaths.
AP Fauci said the nation is averaging 40,000 to 50,000 new cases every day. The US has reported more than 7.8 million cases and 215,085 deaths.

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